Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

Por Starr, Robyn, Metcalf, Donald, Elefanty, Andrew G., Brysha, Marta, Willson, Tracy A., Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S.
Publicado em 1998

Leptin can induce proliferation, differentiation, and functional activation of hemopoietic cells

Por Gainsford, Timothy, Willson, Tracy A., Metcalf, Donald, Handman, Emanuela, McFarlane, Clare, Ng, Ashley, Nicola, Nicos A., Alexander, Warren S., Hilton, Douglas J.
Publicado em 1996

ChIP-seq analysis reveals distinct H3K27me3 profiles that correlate with transcriptional activity

Por Young, Matthew D., Willson, Tracy A., Wakefield, Matthew J., Trounson, Evelyn, Hilton, Douglas J., Blewitt, Marnie E., Oshlack, Alicia, Majewski, Ian J.
Publicado em 2011

SMCHD1's ubiquitin-like domain is required for N-terminal dimerization and chromatin localization

Por Gurzau, Alexandra D., Horne, Christopher R., Mok, Yee-Foong, Iminitoff, Megan, Willson, Tracy A., Young, Samuel N., Blewitt, Marnie E., Murphy, James M.
Publicado no Biochem J (2021)

Twenty proteins containing a C-terminal SOCS box form five structural classes

Por Hilton, Douglas J., Richardson, Rachael T., Alexander, Warren S., Viney, Elizabeth M., Willson, Tracy A., Sprigg, Naomi S., Starr, Robyn, Nicholson, Sandra E., Metcalf, Donald, Nicola, Nicos A.
Publicado em 1998

The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Por Boyle, Kristy, Egan, Paul, Rakar, Steven, Willson, Tracy A., Wicks, Ian P., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Alexander, Warren S., Roberts, Andrew W., Robb, Lorraine
Publicado em 2007

Regulation of hematopoietic stem cells by their mature progeny

Por de Graaf, Carolyn A., Kauppi, Maria, Baldwin, Tracey, D. Hyland, Craig, Metcalf, Donald, Willson, Tracy A., Carpinelli, Marina R., Smyth, Gordon K., Alexander, Warren S., Hilton, Douglas J.
Publicado em 2010

Suppressor of cytokine signaling (SOCS)-5 is a potential negative regulator of epidermal growth factor signaling

Por Nicholson, Sandra E., Metcalf, Donald, Sprigg, Naomi S., Columbus, Ruth, Walker, Francesca, Silva, Anabel, Cary, Dale, Willson, Tracy A., Zhang, Jian-Guo, Hilton, Douglas J., Alexander, Warren S., Nicola, Nicos A.
Publicado em 2005

The SOCS box of suppressor of cytokine signaling-1 is important for inhibition of cytokine action in vivo

Por Zhang, Jian-Guo, Metcalf, Donald, Rakar, Steven, Asimakis, Maria, Greenhalgh, Christopher J., Willson, Tracy A., Starr, Robyn, Nicholson, Sandra E., Carter, Wendy, Alexander, Warren S., Hilton, Douglas J., Nicola, Nicos A.
Publicado em 2001

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

Por Taoudi, Samir, Bee, Thomas, Hilton, Adrienne, Knezevic, Kathy, Scott, Julie, Willson, Tracy A., Collin, Caitlin, Thomas, Tim, Voss, Anne K., Kile, Benjamin T., Alexander, Warren S., Pimanda, John E., Hilton, Douglas J.
Publicado em 2011

Suppressor of Cytokine Signaling (SOCS) 5 Utilises Distinct Domains for Regulation of JAK1 and Interaction with the Adaptor Protein Shc-1

Por Linossi, Edmond M., Chandrashekaran, Indu R., Kolesnik, Tatiana B., Murphy, James M., Webb, Andrew I., Willson, Tracy A., Kedzierski, Lukasz, Bullock, Alex N., Babon, Jeffrey J., Norton, Raymond S., Nicola, Nicos A., Nicholson, Sandra E.
Publicado em 2013

Suppressor of cytokine signaling-3 preferentially binds to the SHP-2-binding site on the shared cytokine receptor subunit gp130

Por Nicholson, Sandra E., De Souza, David, Fabri, Louis J., Corbin, Jason, Willson, Tracy A., Zhang, Jian-Guo, Silva, Anabel, Asimakis, Maria, Farley, Alison, Nash, Andrew D., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Baca, Manuel
Publicado em 2000

Suppressor screen in Mpl(-/-) mice: c-Myb mutation causes supraphysiological production of platelets in the absence of thrombopoietin signaling

Por Carpinelli, Marina R., Hilton, Douglas J., Metcalf, Donald, Antonchuk, Jennifer L., Hyland, Craig D., Mifsud, Sandra L., Di Rago, Ladina, Hilton, Adrienne A., Willson, Tracy A., Roberts, Andrew W., Ramsay, Robert G., Nicola, Nicos A., Alexander, Warren S.
Publicado em 2004

The SPRY domain–containing SOCS box protein SPSB2 targets iNOS for proteasomal degradation

Por Kuang, Zhihe, Lewis, Rowena S., Curtis, Joan M., Zhan, Yifan, Saunders, Bernadette M., Babon, Jeffrey J., Kolesnik, Tatiana B., Low, Andrew, Masters, Seth L., Willson, Tracy A., Kedzierski, Lukasz, Yao, Shenggen, Handman, Emanuela, Norton, Raymond S., Nicholson, Sandra E.
Publicado em 2010

Mutations in the cofilin partner Aip1/Wdr1 cause autoinflammatory disease and macrothrombocytopenia

Por Kile, Benjamin T., Panopoulos, Athanasia D., Stirzaker, Roslynn A., Hacking, Douglas F., Tahtamouni, Lubna H., Willson, Tracy A., Mielke, Lisa A., Henley, Katya J., Zhang, Jian-Guo, Wicks, Ian P., Stevenson, William S., Nurden, Paquita, Watowich, Stephanie S., Justice, Monica J.
Publicado em 2007

Development of hydrocephalus in mice lacking SOCS7

Por Krebs, Danielle L., Metcalf, Donald, Merson, Tobias D., Voss, Anne K., Thomas, Tim, Zhang, Jian-Guo, Rakar, Steven, O'Bryan, Moira K., Willson, Tracy A., Viney, Elizabeth M., Mielke, Lisa A., Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S.
Publicado em 2004

The conserved SOCS box motif in suppressors of cytokine signaling binds to elongins B and C and may couple bound proteins to proteasomal degradation

Por Zhang, Jian-Guo, Farley, Alison, Nicholson, Sandra E., Willson, Tracy A., Zugaro, Lisa M., Simpson, Richard J., Moritz, Robert L., Cary, Dale, Richardson, Rachael, Hausmann, George, Kile, Benjamin T., Kent, Stephen B. H., Alexander, Warren S., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Baca, Manuel
Publicado em 1999

SOCS2 negatively regulates growth hormone action in vitro and in vivo

Por Greenhalgh, Christopher J., Rico-Bautista, Elizabeth, Lorentzon, Mattias, Thaus, Anne L., Morgan, Phillip O., Willson, Tracy A., Zervoudakis, Panagiota, Metcalf, Donald, Street, Ian, Nicola, Nicos A., Nash, Andrew D., Fabri, Louis J., Norstedt, Gunnar, Ohlsson, Claes, Flores-Morales, Amilcar, Alexander, Warren S., Hilton, Douglas J.
Publicado em 2005

Deficiency of 5-hydroxyisourate hydrolase causes hepatomegaly and hepatocellular carcinoma in mice

Por Stevenson, William S., Hyland, Craig D., Zhang, Jian-Guo, Morgan, Phillip O., Willson, Tracy A., Gill, Anthony, Hilton, Adrienne A., Viney, Elizabeth M., Bahlo, Melanie, Masters, Seth L., Hennebry, Sarah, Richardson, Samantha J., Nicola, Nicos A., Metcalf, Donald, Hilton, Douglas J., Roberts, Andrew W., Alexander, Warren S.
Publicado em 2010

Conserved IKAROS-regulated genes associated with B-progenitor acute lymphoblastic leukemia outcome

Por Witkowski, Matthew T., Hu, Yifang, Roberts, Kathryn G., Boer, Judith M., McKenzie, Mark D., Liu, Grace J., Le Grice, Oliver D., Tremblay, Cedric S., Ghisi, Margherita, Willson, Tracy A., Horstmann, Martin A., Aifantis, Iannis, Cimmino, Luisa, Frietze, Seth, den Boer, Monique L., Mullighan, Charles G., Smyth, Gordon K., Dickins, Ross A.
Publicado no J Exp Med (2017)