The SOCS box of suppressor of cytokine signaling-3 contributes to the control of G-CSF responsiveness in vivo

Suppressor of cytokine signaling 3 (SOCS3) is a negative regulator of granulocyte-colony stimulating factor (G-CSF) signaling in vivo. SOCS proteins regulate cytokine signaling by binding, via their SH2 domains, to activated cytokine receptors or their associated Janus kinases. In addition, they bin...

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Hlavní autoři: Boyle, Kristy, Egan, Paul, Rakar, Steven, Willson, Tracy A., Wicks, Ian P., Metcalf, Donald, Hilton, Douglas J., Nicola, Nicos A., Alexander, Warren S., Roberts, Andrew W., Robb, Lorraine
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society of Hematology 2007
Témata:
Hematopoiesis
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC1975836/
https://ncbi.nlm.nih.gov/pubmed/17510322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2007-03-079178
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