Endoglin potentiates nitric oxide synthesis to enhance definitive hematopoiesis

Por Nasrallah, Rabab, Knezevic, Kathy, Thai, Thuan, Thomas, Shane R., Göttgens, Berthold, Lacaud, Georges, Kouskoff, Valerie, Pimanda, John E.
Publicado no Biol Open (2015)

The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

Por Pimanda, John E., Donaldson, Ian J., de Bruijn, Marella F. T. R., Kinston, Sarah, Knezevic, Kathy, Huckle, Liz, Piltz, Sandie, Landry, Josette-Renée, Green, Anthony R., Tannahill, David, Göttgens, Berthold
Publicado em 2007

ERG dependence distinguishes developmental control of hematopoietic stem cell maintenance from hematopoietic specification

Por Taoudi, Samir, Bee, Thomas, Hilton, Adrienne, Knezevic, Kathy, Scott, Julie, Willson, Tracy A., Collin, Caitlin, Thomas, Tim, Voss, Anne K., Kile, Benjamin T., Alexander, Warren S., Pimanda, John E., Hilton, Douglas J.
Publicado em 2011

A Runx1-Smad6 Rheostat Controls Runx1 Activity during Embryonic Hematopoiesis

Por Knezevic, Kathy, Bee, Thomas, Wilson, Nicola K., Janes, Mary E., Kinston, Sarah, Polderdijk, Stéphanie, Kolb-Kokocinski, Anja, Ottersbach, Katrin, Pencovich, Niv, Groner, Yoram, de Bruijn, Marella, Göttgens, Berthold, Pimanda, John E.
Publicado em 2011

cis-Regulatory Remodeling of the SCL Locus during Vertebrate Evolution

Por Göttgens, Berthold, Ferreira, Rita, Sanchez, Maria-José, Ishibashi, Shoko, Li, Juan, Spensberger, Dominik, Lefevre, Pascal, Ottersbach, Katrin, Chapman, Michael, Kinston, Sarah, Knezevic, Kathy, Hoogenkamp, Maarten, Follows, George A., Bonifer, Constanze, Amaya, Enrique, Green, Anthony R.
Publicado em 2010

Gata2, Fli1, and Scl form a recursively wired gene-regulatory circuit during early hematopoietic development

Por Pimanda, John E., Ottersbach, Katrin, Knezevic, Kathy, Kinston, Sarah, Chan, Wan Y. I., Wilson, Nicola K., Landry, Josette-Renée, Wood, Andrew D., Kolb-Kokocinski, Anja, Green, Anthony R., Tannahill, David, Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold
Publicado em 2007

SMAD1 and SMAD5 Expression Is Coordinately Regulated by FLI1 and GATA2 during Endothelial Development

Por Marks-Bluth, Jonathon, Khanna, Anchit, Chandrakanthan, Vashe, Thoms, Julie, Bee, Thomas, Eich, Christina, Kang, Young Chan, Knezevic, Kathy, Qiao, Qiao, Fitch, Simon, Oxburgh, Leif, Ottersbach, Katrin, Dzierzak, Elaine, de Bruijn, Marella F. T. R., Pimanda, John E.
Publicado no Mol Cell Biol (2015)

The scl +18/19 Stem Cell Enhancer Is Not Required for Hematopoiesis: Identification of a 5′ Bifunctional Hematopoietic-Endothelial Enhancer Bound by Fli-1 and Elf-1

Por Göttgens, Berthold, Broccardo, Cyril, Sanchez, Maria-Jose, Deveaux, Sophie, Murphy, George, Göthert, Joachim R., Kotsopoulou, Ekaterini, Kinston, Sarah, Delaney, Liz, Piltz, Sandie, Barton, Linda M., Knezevic, Kathy, Erber, Wendy N., Begley, C. Glenn, Frampton, Jonathan, Green, Anthony R.
Publicado em 2004

DKC1 is a transcriptional target of GATA1 and drives upregulation of telomerase activity in normal human erythroblasts

Por Richards, Laura A., Kumari, Ashu, Knezevic, Kathy, Thoms, Julie AI, von Jonquieres, Georg, Napier, Christine E., Ali, Zara, O’Brien, Rosemary, Marks-Bluth, Jonathon, Maritz, Michelle F., Pickett, Hilda A, Morris, Jonathan, Pimanda, John E., MacKenzie, Karen L.
Publicado no Haematologica (2020)

Endoglin Expression in Blood and Endothelium is Differentially Regulated by Modular Assembly of the Ets/Gata Hemangioblast Code

Por Pimanda, John E., Chan, Wan Y.I., Wilson, Nicola K., Smith, Aileen M., Kinston, Sarah, Knezevic, Kathy, Janes, Mary E., Landry, Josette-Renée, Kolb-Kokocinski, Anja, Frampton, Jonathan, Tannahill, David, Ottersbach, Katrin, Follows, George A., Lacaud, Georges, Kouskoff, Valerie, Göttgens, Berthold
Publicado em 2008

Genome-scale expression and transcription factor binding profiles reveal therapeutic targets in transgenic ERG myeloid leukemia

Por Goldberg, Liat, Tijssen, Marloes R., Birger, Yehudit, Hannah, Rebecca L., Kinston, Sarah J., Schütte, Judith, Beck, Dominik, Knezevic, Kathy, Schiby, Ginette, Jacob-Hirsch, Jasmine, Biran, Anat, Kloog, Yoel, Marcucci, Guido, Bloomfield, Clara D., Aplan, Peter D., Pimanda, John E., Göttgens, Berthold, Izraeli, Shai
Publicado em 2013

A quantitative proteomics approach identifies ETV6 and IKZF1 as new regulators of an ERG-driven transcriptional network

Por Unnikrishnan, Ashwin, Guan, Yi F., Huang, Yizhou, Beck, Dominik, Thoms, Julie A. I., Peirs, Sofie, Knezevic, Kathy, Ma, Shiyong, de Walle, Inge V., de Jong, Ineke, Ali, Zara, Zhong, Ling, Raftery, Mark J., Taghon, Tom, Larsson, Jonas, MacKenzie, Karen L., Van Vlierberghe, Pieter, Wong, Jason W. H., Pimanda, John E.
Publicado no Nucleic Acids Res (2016)

Arrested Hematopoiesis and Vascular Relaxation Defects in Mice with a Mutation in Dhfr

Por Thoms, Julie A. I., Knezevic, Kathy, Liu, Jia Jenny, Glaros, Elias N., Thai, Thuan, Qiao, Qiao, Campbell, Heather, Packham, Deborah, Huang, Yizhou, Papathanasiou, Peter, Tunningley, Robert, Whittle, Belinda, Yeung, Amanda W. S., Chandrakanthan, Vashe, Hesson, Luke, Chen, Vivien, Wong, Jason W. H., Purton, Louise E., Ward, Robyn L., Thomas, Shane R., Pimanda, John E.
Publicado no Mol Cell Biol (2016)

Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Por Nasrallah, Rabab, Fast, Eva M., Solaimani, Parham, Knezevic, Kathy, Eliades, Alexia, Patel, Rahima, Thambyrajah, Roshana, Unnikrishnan, Ashwin, Thoms, Julie, Beck, Dominik, Vink, Chris S., Smith, Aileen, Wong, Jason, Shepherd, Mairi, Kent, David, Roychoudhuri, Rahul, Paul, Fabian, Klippert, Julia, Hammes, Annette, Willnow, Thomas, Göttgens, Bertie, Dzierzak, Elaine, Zon, Leonard I., Lacaud, George, Kouskoff, Valerie, Pimanda, John E.
Publicado no Blood (2016)

PDGF-AB and 5-Azacytidine induce conversion of somatic cells into tissue-regenerative multipotent stem cells

Por Chandrakanthan, Vashe, Yeola, Avani, Kwan, Jair C., Oliver, Rema A., Qiao, Qiao, Kang, Young Chan, Zarzour, Peter, Beck, Dominik, Boelen, Lies, Unnikrishnan, Ashwin, Villanueva, Jeanette E., Nunez, Andrea C., Knezevic, Kathy, Palu, Cintia, Nasrallah, Rabab, Carnell, Michael, Macmillan, Alex, Whan, Renee, Yu, Yan, Hardy, Philip, Grey, Shane T., Gladbach, Amadeus, Delerue, Fabien, Ittner, Lars, Mobbs, Ralph, Walkley, Carl R., Purton, Louise E., Ward, Robyn L., Wong, Jason W. H., Hesson, Luke B., Walsh, William, Pimanda, John E.
Publicado no Proc Natl Acad Sci U S A (2016)

The EMT modulator SNAI1 contributes to AML pathogenesis via its interaction with LSD1

Por Carmichael, Catherine L., Wang, Jueqiong, Nguyen, Thao, Kolawole, Oluseyi, Benyoucef, Aissa, De Mazière, Charlotte, Milne, Anna R., Samuel, Sona, Gillinder, Kevin, Hediyeh-zadeh, Soroor, Vo, Anh N. Q., Huang, Yizhou, Knezevic, Kathy, McInnes, William R. L., Shields, Benjamin J., Mitchell, Helen, Ritchie, Matthew E., Lammens, Tim, Lintermans, Beatrice, Van Vlierberghe, Pieter, Wong, Nicholas C., Haigh, Katharina, Thoms, Julie A. I., Toulmin, Emma, Curtis, David J., Oxley, Ethan P., Dickins, Ross A., Beck, Dominik, Perkins, Andrew, McCormack, Matthew P., Davis, Melissa J., Berx, Geert, Zuber, Johannes, Pimanda, John E., Kile, Benjamin T., Goossens, Steven, Haigh, Jody J.
Publicado no Blood (2020)