Identification of novel regulators of developmental hematopoiesis using Endoglin regulatory elements as molecular probes

Enhancers are the primary determinants of cell identity, and specific promoter/enhancer combinations of Endoglin (ENG) have been shown to target blood and endothelium in the embryo. Here, we generated a series of embryonic stem cell lines, each targeted with reporter constructs driven by specific pr...

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Publicado en:Blood
Main Authors: Nasrallah, Rabab, Fast, Eva M., Solaimani, Parham, Knezevic, Kathy, Eliades, Alexia, Patel, Rahima, Thambyrajah, Roshana, Unnikrishnan, Ashwin, Thoms, Julie, Beck, Dominik, Vink, Chris S., Smith, Aileen, Wong, Jason, Shepherd, Mairi, Kent, David, Roychoudhuri, Rahul, Paul, Fabian, Klippert, Julia, Hammes, Annette, Willnow, Thomas, Göttgens, Bertie, Dzierzak, Elaine, Zon, Leonard I., Lacaud, George, Kouskoff, Valerie, Pimanda, John E.
Formato: Artigo
Idioma:Inglês
Publicado: American Society of Hematology 2016
Assuntos:
Hematopoiesis and Stem Cells
Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC5064716/
https://ncbi.nlm.nih.gov/pubmed/27554085
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1182/blood-2016-02-697870
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