The SCL transcriptional network and BMP signaling pathway interact to regulate RUNX1 activity

Hematopoietic stem cell (HSC) development is regulated by several signaling pathways and a number of key transcription factors, which include Scl/Tal1, Runx1, and members of the Smad family. However, it remains unclear how these various determinants interact. Using a genome-wide computational screen...

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Détails bibliographiques
Auteurs principaux: Pimanda, John E., Donaldson, Ian J., de Bruijn, Marella F. T. R., Kinston, Sarah, Knezevic, Kathy, Huckle, Liz, Piltz, Sandie, Landry, Josette-Renée, Green, Anthony R., Tannahill, David, Göttgens, Berthold
Format: Artigo
Langue:Inglês
Publié: National Academy of Sciences 2007
Sujets:
Biological Sciences
Accès en ligne:https://ncbi.nlm.nih.gov/pmc/articles/PMC1783401/
https://ncbi.nlm.nih.gov/pubmed/17213321
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.0607196104
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