The scl +18/19 Stem Cell Enhancer Is Not Required for Hematopoiesis: Identification of a 5′ Bifunctional Hematopoietic-Endothelial Enhancer Bound by Fli-1 and Elf-1

Analysis of cis-regulatory elements is central to understanding the genomic program for development. The scl/tal-1 transcription factor is essential for lineage commitment to blood cell formation and previous studies identified an scl enhancer (the +18/19 element) which was sufficient to target the...

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Hlavní autoři: Göttgens, Berthold, Broccardo, Cyril, Sanchez, Maria-Jose, Deveaux, Sophie, Murphy, George, Göthert, Joachim R., Kotsopoulou, Ekaterini, Kinston, Sarah, Delaney, Liz, Piltz, Sandie, Barton, Linda M., Knezevic, Kathy, Erber, Wendy N., Begley, C. Glenn, Frampton, Jonathan, Green, Anthony R.
Médium: Artigo
Jazyk:Inglês
Vydáno: American Society for Microbiology 2004
Témata:
Transcriptional Regulation
On-line přístup:https://ncbi.nlm.nih.gov/pmc/articles/PMC350551/
https://ncbi.nlm.nih.gov/pubmed/14966269
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.24.5.1870-1883.2004
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