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Deletion of the Scl +19 enhancer increases the blood stem cell compartment without affecting the formation of mature blood lineages
The stem cell leukemia (Scl)/Tal1 gene is essential for normal blood and endothelial development, and is expressed in hematopoietic stem cells (HSCs), progenitors, erythroid, megakaryocytic, and mast cells. The Scl +19 enhancer is active in HSCs and progenitor cells, megakaryocytes, and mast cells,...
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| Autors principals: | , , , , , , , , |
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| Format: | Artigo |
| Idioma: | Inglês |
| Publicat: |
Elsevier Science Inc
2012
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| Matèries: | |
| Accés en línia: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3387379/ https://ncbi.nlm.nih.gov/pubmed/22401818 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.exphem.2012.02.006 |
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