Transcriptional regulation of Elf-1: locus-wide analysis reveals four distinct promoters, a tissue-specific enhancer, control by PU.1 and the importance of Elf-1 downregulation for erythroid maturation

Ets transcription factors play important roles during the development and maintenance of the haematopoietic system. One such factor, Elf-1 (E74-like factor 1) controls the expression of multiple essential haematopoietic regulators including Scl/Tal1, Lmo2 and PU.1. However, to integrate Elf-1 into t...

وصف كامل

محفوظ في:
التفاصيل البيبلوغرافية
المؤلفون الرئيسيون: Calero-Nieto, Fernando J., Wood, Andrew D., Wilson, Nicola K., Kinston, Sarah, Landry, Josette-Renée, Göttgens, Berthold
التنسيق: Artigo
اللغة:Inglês
منشور في: Oxford University Press 2010
الموضوعات:
Gene Regulation, Chromatin and Epigenetics
الوصول للمادة أونلاين:https://ncbi.nlm.nih.gov/pmc/articles/PMC2965225/
https://ncbi.nlm.nih.gov/pubmed/20525788
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/nar/gkq490
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