Runx1 promotes murine erythroid progenitor proliferation and inhibits differentiation by preventing Pu.1 downregulation

Pu.1 is an ETS family transcription factor (TF) that plays critical roles in erythroid progenitors by promoting proliferation and blocking terminal differentiation. However, the mechanisms controlling expression and down-regulation of Pu.1 during early erythropoiesis have not been defined. In this s...

Полное описание

Сохранить в:
Библиографические подробности
Опубликовано в: :Proc Natl Acad Sci U S A
Главные авторы: Willcockson, Michael A., Taylor, Samuel J., Ghosh, Srikanta, Healton, Sean E., Wheat, Justin C., Wilson, Tommy J., Steidl, Ulrich, Skoultchi, Arthur I.
Формат: Artigo
Язык:Inglês
Опубликовано: National Academy of Sciences 2019
Предметы:
Biological Sciences
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC6731665/
https://ncbi.nlm.nih.gov/pubmed/31431533
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1073/pnas.1901122116
Метки: Добавить метку
Нет меток, Требуется 1-ая метка записи!

Схожие документы