PU.1 and pRB Interact and Cooperate To Repress GATA-1 and Block Erythroid Differentiation

PU.1 and GATA-1 are two hematopoietic specific transcription factors that play key roles in development of the myeloid and erythroid lineages, respectively. The two proteins bind to one another and inhibit each other's function in transcriptional activation and promotion of their respective dif...

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Autori principali: Rekhtman, Natasha, Choe, Kevin S., Matushansky, Igor, Murray, Stuart, Stopka, Tomas, Skoultchi, Arthur I.
Natura: Artigo
Lingua:Inglês
Pubblicazione: American Society for Microbiology 2003
Soggetti:
Transcriptional Regulation
Accesso online:https://ncbi.nlm.nih.gov/pmc/articles/PMC207581/
https://ncbi.nlm.nih.gov/pubmed/14559995
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/MCB.23.21.7460-7474.2003
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