Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

Stem cells are a central feature of metazoan biology. Haematopoietic stem cells (HSCs) represent the best-characterized example of this phenomenon, but the molecular mechanisms responsible for their formation remain obscure. The stem cell leukaemia (SCL) gene encodes a basic helix–loop–helix (bHLH)...

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Detalhes bibliográficos
Main Authors: Göttgens, Berthold, Nastos, Aristotelis, Kinston, Sarah, Piltz, Sandie, Delabesse, Eric C.M., Stanley, Maureen, Sanchez, Maria-Jose, Ciau-Uitz, Aldo, Patient, Roger, Green, Anthony R.
Formato: Artigo
Idioma:Inglês
Publicado em: Oxford University Press 2002
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Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC126046/
https://ncbi.nlm.nih.gov/pubmed/12065417
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1093/emboj/cdf286
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