Establishing the transcriptional programme for blood: the SCL stem cell enhancer is regulated by a multiprotein complex containing Ets and GATA factors

Stem cells are a central feature of metazoan biology. Haematopoietic stem cells (HSCs) represent the best-characterized example of this phenomenon, but the molecular mechanisms responsible for their formation remain obscure. The stem cell leukaemia (SCL) gene encodes a basic helix–loop–helix (bHLH)...

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Pubblicato in:	EMBO J
Autori principali:	Göttgens, Berthold, Nastos, Aristotelis, Kinston, Sarah, Piltz, Sandie, Delabesse, Eric C.M., Stanley, Maureen, Sanchez, Maria-Jose, Ciau-Uitz, Aldo, Patient, Roger, Green, Anthony R.
Natura:	Artigo
Lingua:	Inglês
Pubblicazione:	Nature Publishing Group 2002
Soggetti:	Article
Accesso online:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC126046/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/12065417/ https://ncbi.nlm.nih.govhttps://doi.org/10.1093/emboj/cdf286
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