Liver degeneration and lymphoid deficiencies in mice lacking suppressor of cytokine signaling-1

SOCS-1, a member of the suppressor of cytokine signaling (SOCS) family, was identified in a genetic screen for inhibitors of interleukin 6 signal transduction. SOCS-1 transcription is induced by cytokines, and the protein binds and inhibits Janus kinases and reduces cytokine-stimulated tyrosine phos...

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Detalhes bibliográficos

Publicado no:	Proc Natl Acad Sci U S A
Principais autores:	Starr, Robyn, Metcalf, Donald, Elefanty, Andrew G., Brysha, Marta, Willson, Tracy A., Nicola, Nicos A., Hilton, Douglas J., Alexander, Warren S.
Formato:	Artigo
Idioma:	Inglês
Publicado em:	National Academy of Sciences 1998
Assuntos:	Biological Sciences
Acesso em linha:	https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC24384/ https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/9826711/ https://ncbi.nlm.nih.govhttps://doi.org/10.1073/pnas.95.24.14395
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