Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

von Drewry, David H., Willson, Timothy M., Zuercher, William J.
Veröffentlicht in Curr Top Med Chem (2014)

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

von Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
Veröffentlicht in Sci Rep (2019)

Chemical Approaches to Nuclear Receptors in Metabolism

von Margolis, Ronald N., Moore, David D., Willson, Timothy M., Guy, R. Kip
Veröffentlicht in Sci Signal (2009)

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

von Drewry, David H., Wells, Carrow I., Zuercher, William J., Willson, Timothy M.
Veröffentlicht in SLAS Discov (2019)

Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.

von O’Byrne, Sean N., Eduful, Benjamin J., Willson, Timothy M., Drewry, David H.
Veröffentlicht in Tetrahedron Lett (2020)

The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily

von Maglich, Jodi M., Caravella, Justin A., Lambert, Millard H., Willson, Timothy M., Moore, John T., Ramamurthy, Lakshman
Veröffentlicht 2003

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

von Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.
Veröffentlicht 2006

Activation of the orphan receptor RIP14 by retinoids

von Zavacki, Ann Marie, Lehmann, Jürgen M., Seol, Wongi, Willson, Timothy M., Kliewer, Steven A., Moore, David D.
Veröffentlicht 1997

Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

von Li, Andrew C., Brown, Kathleen K., Silvestre, Mercedes J., Willson, Timothy M., Palinski, Wulf, Glass, Christopher K.
Veröffentlicht 2000

Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia

von Zhang, Yanqiao, Yin, Liya, Anderson, Jody, Ma, Huiyan, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Veröffentlicht 2010

Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation...

von Sastre, Magdalena, Dewachter, Ilse, Landreth, Gary E., Willson, Timothy M., Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T.
Veröffentlicht in J Neurosci (2003)

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor γ1

von Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley
Veröffentlicht 2001

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

von Zhang, Yanqiao, Lee, Florence Ying, Barrera, Gabriel, Lee, Hans, Vales, Charisse, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Veröffentlicht 2006

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ

von Ghisletti, Serena, Huang, Wendy, Ogawa, Sumito, Pascual, Gabriel, Lin, Mu-En, Willson, Timothy M., Rosenfeld, Michael G., Glass, Christopher K.
Veröffentlicht 2007

Ligand Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) Inhibits Cell Growth of Human N/TERT-1 Keratinocytes

von Burdick, Andrew D., Bility, Moses T., Girroir, Elizabeth E., Billin, Andrew N., Willson, Timothy M., Gonzalez, Frank J., Peters, Jeffrey M.
Veröffentlicht 2007

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer

von Gupta, Rajnish A., Tan, Jian, Krause, Wade F., Geraci, Mark W., Willson, Timothy M., Dey, Sudhansu K., DuBois, Raymond N.
Veröffentlicht 2000

Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes

von Maglich, Jodi M, Sluder, Ann, Guan, Xiaojun, Shi, Yunling, McKee, David D, Carrick, Kevin, Kamdar, Kim, Willson, Timothy M, Moore, John T
Veröffentlicht 2001

The p300 Acetylase Is Critical for Ligand-activated Farnesoid X Receptor (FXR) Induction of SHP

von Fang, Sungsoon, Tsang, Stephanie, Jones, Ryan, Ponugoti, Bhaskar, Yoon, Hyeryoung, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Willson, Timothy M., Kemper, Jongsook Kim
Veröffentlicht 2008

Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets

von Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis
Veröffentlicht 2014

Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor. VOLUME 278 (2003) PAGES 20420-20428

von Anisfeld, Andrew M., Kast-Woelbern, Heidi R., Meyer, Marie E., Jones, Stacey A., Zhang, Yanqiao, Williams, Kevin J., Willson, Timothy, Edwards, Peter A.
Veröffentlicht 2009