Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia

Farnesoid X receptor (FXR) plays important regulatory roles in bile acid, lipoprotein, and glucose homeostasis. Here, we have utilized Fxr(−/−) mice and mice deficient in scavenger receptor class B type I (SR-BI), together with an FXR-specific agonist and adenovirus expressing hepatocyte nuclear fac...

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Bibliografske podrobnosti
Main Authors: Zhang, Yanqiao, Yin, Liya, Anderson, Jody, Ma, Huiyan, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Format: Artigo
Jezik:Inglês
Izdano: American Society for Biochemistry and Molecular Biology 2010
Teme:
Metabolism and Bioenergetics
Online dostop:https://ncbi.nlm.nih.gov/pmc/articles/PMC2823426/
https://ncbi.nlm.nih.gov/pubmed/19996107
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M109.083899
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