Activation of the Farnesoid X Receptor Induces Hepatic Expression and Secretion of Fibroblast Growth Factor 21

Previous studies have shown that starvation or consumption of a high fat, low carbohydrate (HF-LC) ketogenic diet induces hepatic fibroblast growth factor 21 (FGF21) gene expression in part by activating the peroxisome proliferator-activated receptor-α (PPARα). Using primary hepatocyte cultures to s...

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Bibliographische Detailangaben
Hauptverfasser: Cyphert, Holly A., Ge, Xuemei, Kohan, Alison B., Salati, Lisa M., Zhang, Yanqiao, Hillgartner, F. Bradley
Format: Artigo
Sprache:Inglês
Veröffentlicht: American Society for Biochemistry and Molecular Biology 2012
Schlagworte:
Metabolism
Online Zugang:https://ncbi.nlm.nih.gov/pmc/articles/PMC3408207/
https://ncbi.nlm.nih.gov/pubmed/22661717
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1074/jbc.M112.375907
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