A Novel Strategy to Mitigate the Hyperinflammatory Response to COVID-19 by Targeting Leukotrienes

Por Funk, Colin D., Ardakani, Ali
Publicado no Front Pharmacol (2020)

A Snapshot of the Global Race for Vaccines Targeting SARS-CoV-2 and the COVID-19 Pandemic

Por Funk, Colin D., Laferrière, Craig, Ardakani, Ali
Publicado no Front Pharmacol (2020)

Target Product Profile Analysis of COVID-19 Vaccines in Phase III Clinical Trials and Beyond: An Early 2021 Perspective

Por Funk, Colin D., Laferrière, Craig, Ardakani, Ali
Publicado no Viruses (2021)

Increased platelet sensitivity to ADP in mice lacking platelet-type 12-lipoxygenase

Por Johnson, Eric N., Brass, Lawrence F., Funk, Colin D.
Publicado em 1998

Pulmonary Oxidative Stress Is Increased in Cyclooxygenase-2 Knockdown Mice with Mild Pulmonary Hypertension Induced by Monocrotaline

Por Seta, Francesca, Rahmani, Mahboubeh, Turner, Patricia V., Funk, Colin D.
Publicado em 2011

Perivascular adipose tissue–derived extracellular vesicle miR-221-3p mediates vascular remodeling

Por Li, Xinzhi, Ballantyne, Laurel L., Yu, Ying, Funk, Colin D.
Publicado no FASEB J (2019)

Absence of 12/15 Lipoxygenase Reduces Brain Oxidative Stress in Apolipoprotein E-Deficient Mice

Por Chinnici, Cinzia M., Yao, Yuemang, Ding, Tao, Funk, Colin D., Praticò, Domenico
Publicado em 2005

Dual 12/15- and 5-Lipoxygenase Deficiency in Macrophages Alters Arachidonic Acid Metabolism and Attenuates Peritonitis and Atherosclerosis in ApoE Knock-out Mice

Por Poeckel, Daniel, Zemski Berry, Karin A., Murphy, Robert C., Funk, Colin D.
Publicado em 2009

Proof-of-Concept Gene Editing for the Murine Model of Inducible Arginase-1 Deficiency

Por Sin, Yuan Yan, Price, Phillipe R., Ballantyne, Laurel L., Funk, Colin D.
Publicado no Sci Rep (2017)

Transplantation of Gene-Edited Hepatocyte-like Cells Modestly Improves Survival of Arginase-1-Deficient Mice

Por Sin, Yuan Yan, Ballantyne, Laurel L., Richmond, Christopher R., Funk, Colin D.
Publicado no Mol Ther Nucleic Acids (2017)

The Murine Angiotensin II-Induced Abdominal Aortic Aneurysm Model: Rupture Risk and Inflammatory Progression Patterns

Por Cao, Richard Y., Amand, Tim, Ford, Matthew D., Piomelli, Ugo, Funk, Colin D.
Publicado em 2010

Actin Polymerization in Macrophages in Response to Oxidized LDL and Apoptotic Cells: Role of 12/15-Lipoxygenase and Phosphoinositide 3-Kinase

Por Miller, Yury I., Worrall, Dorothy S., Funk, Colin D., Feramisco, James R., Witztum, Joseph L.
Publicado em 2003

Resistance to type 1 diabetes induction in 12-lipoxygenase knockout mice

Por Bleich, David, Chen, Songyuan, Zipser, Brian, Sun, Duxin, Funk, Colin D., Nadler, Jerry L.
Publicado em 1999

Effects of p53-knockout in vascular smooth muscle cells on atherosclerosis in mice

Por Cao, Richard Yang, Eves, Robert, Jia, Lilly, Funk, Colin D., Jia, Zongchao, Mak, Alan S.
Publicado no PLoS One (2017)

Role of decay-accelerating factor in regulating complement activation on the erythrocyte surface as revealed by gene targeting

Por Sun, Xiujun, Funk, Colin D., Deng, Chengjun, Sahu, Arvind, Lambris, John D., Song, Wen-Chao
Publicado em 1999

Cyclooxygenases, microsomal prostaglandin E synthase-1, and cardiovascular function

Por Cheng, Yan, Wang, Miao, Yu, Ying, Lawson, John, Funk, Colin D., FitzGerald, Garret A.
Publicado em 2006

Genomic and lipidomic analyses differentiate the compensatory roles of two COX isoforms during systemic inflammation in mice(1),(2)

Por Li, Xinzhi, Mazaleuskaya, Liudmila L., Ballantyne, Laurel L., Meng, Hu, FitzGerald, Garret A., Funk, Colin D.
Publicado no J Lipid Res (2018)

Differential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions

Por Li, Xinzhi, Mazaleuskaya, Liudmila L., Ballantyne, Laurel L., Meng, Hu, FitzGerald, Garret A., Funk, Colin D.
Publicado no FASEB J (2018)

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor γ1

Por Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley
Publicado em 2001

Characterization of the Cysteinyl Leukotriene 2 Receptor in Novel Expression Sites of the Gastrointestinal Tract

Por Barajas-Espinosa, Alma, Ochoa-Cortes, Fernando, Moos, Michael P., Daniel Ramirez, F., Vanner, Stephen J., Funk, Colin D.
Publicado em 2011