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Actin Polymerization in Macrophages in Response to Oxidized LDL and Apoptotic Cells: Role of 12/15-Lipoxygenase and Phosphoinositide 3-Kinase

Formation of filamentous F-actin drives many cellular processes, including phagocytosis and cell spreading. We have recently reported that mouse macrophage 12/15-lipoxygenase (12/15-LO) activity promotes F-actin formation in filopodia during phagocytosis of apoptotic cells. Oxidized low-density lipo...

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Detalhes bibliográficos
Main Authors: Miller, Yury I., Worrall, Dorothy S., Funk, Colin D., Feramisco, James R., Witztum, Joseph L.
Formato: Artigo
Idioma:Inglês
Publicado em: The American Society for Cell Biology 2003
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC207011/
https://ncbi.nlm.nih.gov/pubmed/14517329
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1091/mbc.E03-02-0063
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