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Differential compensation of two cyclooxygenases in renal homeostasis is independent of prostaglandin-synthetic capacity under basal conditions

The distinct functions of each cyclooxygenase (COX) isoform in renal homeostasis have been the subject of intense investigation for many years. We took the novel approach of using 3 characterized mouse lines, where the prostaglandin (PG)-endoperoxide synthase genes 1 and 2 (Ptgs1 and Ptgs2) substitu...

詳細記述

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書誌詳細
出版年:FASEB J
主要な著者: Li, Xinzhi, Mazaleuskaya, Liudmila L., Ballantyne, Laurel L., Meng, Hu, FitzGerald, Garret A., Funk, Colin D.
フォーマット: Artigo
言語:Inglês
出版事項: Federation of American Societies for Experimental Biology 2018
主題:
オンライン・アクセス:https://ncbi.nlm.nih.gov/pmc/articles/PMC6133703/
https://ncbi.nlm.nih.gov/pubmed/29676940
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1096/fj.201800252R
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