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Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

Development of an efficient and scalable synthesis of 6-formylindolo[3,2-b]carbazole (FICZ), a naturally-occurring aryl hydrocarbon receptor (AhR) ligand, allowed its biological and physical properties to be studied. FICZ was shown to be the most potent among a series of 6-substituted indolo[3,2-b]c...

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Detalhes bibliográficos
Publicado no:Sci Rep
Main Authors: Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
Formato: Artigo
Idioma:Inglês
Publicado em: Nature Publishing Group UK 2019
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Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6620467/
https://ncbi.nlm.nih.gov/pubmed/31292477
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/s41598-019-46374-7
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