Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

Por Drewry, David H., Willson, Timothy M., Zuercher, William J.
Publicado no Curr Top Med Chem (2014)

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

Por Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
Publicado no Sci Rep (2019)

Chemical Approaches to Nuclear Receptors in Metabolism

Por Margolis, Ronald N., Moore, David D., Willson, Timothy M., Guy, R. Kip
Publicado no Sci Signal (2009)

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

Por Drewry, David H., Wells, Carrow I., Zuercher, William J., Willson, Timothy M.
Publicado no SLAS Discov (2019)

Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.

Por O’Byrne, Sean N., Eduful, Benjamin J., Willson, Timothy M., Drewry, David H.
Publicado no Tetrahedron Lett (2020)

The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily

Por Maglich, Jodi M., Caravella, Justin A., Lambert, Millard H., Willson, Timothy M., Moore, John T., Ramamurthy, Lakshman
Publicado em 2003

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

Por Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.
Publicado em 2006

Activation of the orphan receptor RIP14 by retinoids

Por Zavacki, Ann Marie, Lehmann, Jürgen M., Seol, Wongi, Willson, Timothy M., Kliewer, Steven A., Moore, David D.
Publicado em 1997

Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

Por Li, Andrew C., Brown, Kathleen K., Silvestre, Mercedes J., Willson, Timothy M., Palinski, Wulf, Glass, Christopher K.
Publicado em 2000

Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia

Por Zhang, Yanqiao, Yin, Liya, Anderson, Jody, Ma, Huiyan, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Publicado em 2010

Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation...

Por Sastre, Magdalena, Dewachter, Ilse, Landreth, Gary E., Willson, Timothy M., Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T.
Publicado no J Neurosci (2003)

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor γ1

Por Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley
Publicado em 2001

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

Por Zhang, Yanqiao, Lee, Florence Ying, Barrera, Gabriel, Lee, Hans, Vales, Charisse, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Publicado em 2006

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ

Por Ghisletti, Serena, Huang, Wendy, Ogawa, Sumito, Pascual, Gabriel, Lin, Mu-En, Willson, Timothy M., Rosenfeld, Michael G., Glass, Christopher K.
Publicado em 2007

Ligand Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) Inhibits Cell Growth of Human N/TERT-1 Keratinocytes

Por Burdick, Andrew D., Bility, Moses T., Girroir, Elizabeth E., Billin, Andrew N., Willson, Timothy M., Gonzalez, Frank J., Peters, Jeffrey M.
Publicado em 2007

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer

Por Gupta, Rajnish A., Tan, Jian, Krause, Wade F., Geraci, Mark W., Willson, Timothy M., Dey, Sudhansu K., DuBois, Raymond N.
Publicado em 2000

Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes

Por Maglich, Jodi M, Sluder, Ann, Guan, Xiaojun, Shi, Yunling, McKee, David D, Carrick, Kevin, Kamdar, Kim, Willson, Timothy M, Moore, John T
Publicado em 2001

The p300 Acetylase Is Critical for Ligand-activated Farnesoid X Receptor (FXR) Induction of SHP

Por Fang, Sungsoon, Tsang, Stephanie, Jones, Ryan, Ponugoti, Bhaskar, Yoon, Hyeryoung, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Willson, Timothy M., Kemper, Jongsook Kim
Publicado em 2008

Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets

Por Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis
Publicado em 2014

Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor. VOLUME 278 (2003) PAGES 20420-20428

Por Anisfeld, Andrew M., Kast-Woelbern, Heidi R., Meyer, Marie E., Jones, Stacey A., Zhang, Yanqiao, Williams, Kevin J., Willson, Timothy, Edwards, Peter A.
Publicado em 2009