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Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ

Transrepression is widely utilized to negatively regulate gene expression, but the mechanisms by which different nuclear receptors effect gene- and signal-specific transrepression programs remain poorly understood. Here, we report the identification of alternative SUMOylation-dependent mechanisms th...

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Detalhes bibliográficos
Main Authors: Ghisletti, Serena, Huang, Wendy, Ogawa, Sumito, Pascual, Gabriel, Lin, Mu-En, Willson, Timothy M., Rosenfeld, Michael G., Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado em: 2007
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC1850387/
https://ncbi.nlm.nih.gov/pubmed/17218271
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molcel.2006.11.022
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