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A sumoylation-dependent pathway mediating transrepression of inflammatory response genes by PPARγ

The peroxisome proliferator-activated receptor γ (PPARγ) plays essential roles in adipogenesis and glucose homeostasis and is a molecular target of insulin-sensitizing drugs1–3. Although the ability of PPARγ agonists to antagonize inflammatory responses by transrepression of nuclear factor kappaB (N...

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Main Authors: Pascual, Gabriel, Fong, Amy L., Ogawa, Sumito, Gamliel, Amir, Li, Andrew C., Perissi, Valentina, Rose, David W., Willson, Timothy, Rosenfeld, Michael G., Glass, Christopher K.
Formato: Artigo
Idioma:Inglês
Publicado: 2005
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Acceso en liña:https://ncbi.nlm.nih.gov/pmc/articles/PMC1464798/
https://ncbi.nlm.nih.gov/pubmed/16127449
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1038/nature03988
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