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Sumoylation of PPARγ by apoptotic cells prevents LPS-induced NCoR removal from κB binding sites mediating transrepression of pro-inflammatory cytokines
Efficient clearance of apoptotic cells (AC) by professional phagocytes is crucial for tissue homeostasis and resolution of inflammation. Macrophages respond to AC with an increase in anti-inflammatory cytokine production, but a diminished release of pro-inflammatory mediators. Mechanisms to explain...
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| Main Authors: | , , , , , , |
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| Formato: | Artigo |
| Idioma: | Inglês |
| Publicado em: |
2008
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| Assuntos: | |
| Acesso em linha: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2679654/ https://ncbi.nlm.nih.gov/pubmed/18832723 |
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