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Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

The peroxisome proliferator–activated receptor γ (PPARγ) is a nuclear receptor that regulates fat-cell development and glucose homeostasis and is the molecular target of a class of insulin-sensitizing agents used for the management of type 2 diabetes mellitus. PPARγ is highly expressed in macrophage...

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Bibliographic Details
Published in:J Clin Invest
Main Authors: Li, Andrew C., Brown, Kathleen K., Silvestre, Mercedes J., Willson, Timothy M., Palinski, Wulf, Glass, Christopher K.
Format: Artigo
Language:Inglês
Published: American Society for Clinical Investigation 2000
Subjects:
Online Access:https://ncbi.nlm.nih.govhttps://pmc.ncbi.nlm.nih.gov/articles/PMC380255/
https://ncbi.nlm.nih.govhttps://pubmed.ncbi.nlm.nih.gov/10953027/
https://ncbi.nlm.nih.govhttps://doi.org/10.1172/JCI10370
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