Rab GTPases as Physiological Substrates of LRRK2 Kinase

Por Seol, Wongi, Nam, Daleum, Son, Ilhong
Publicado no Exp Neurobiol (2019)

Upregulation of the p53-p21 pathway by G2019S LRRK2 contributes to the cellular senescence and accumulation of α-synuclein

Por Ho, Dong Hwan, Seol, Wongi, Son, Ilhong
Publicado no Cell Cycle (2019)

Coordinate Regulation of Neurite Outgrowth by LRRK2 and Its Interactor, Rab5

Por Heo, Hye Young, Kim, Kwang-Soo, Seol, Wongi
Publicado em 2010

G2019s LRRK2 promotes mitochondrial fission and increases TNFα-mediated neuroinflammation responses

Por Ho, Dong Hwan, Lee, Heajin, Son, Ilhong, Seol, Wongi
Publicado no Anim Cells Syst (Seoul) (2019)

Induction and characterization of taxol-resistance phenotypes with a transiently expressed artificial transcriptional activator library

Por Lee, Dong-ki, Kim, Yong Ha, Kim, Jin-Soo, Seol, Wongi
Publicado em 2004

Increased DJ-1 in Urine Exosome of Korean Males with Parkinson's Disease

Por Ho, Dong Hwan, Yi, Sanghak, Seo, Hyemyung, Son, Ilhong, Seol, Wongi
Publicado no Biomed Res Int (2014)

Expression of the LRRK 2 gene in the midbrain dopaminergic neurons of the substantia nigra

Por Han, Baek-Soo, Iacovitti, Lorraine, Katano, Taku, Hattori, Nobutaka, Seol, Wongi, Kim, Kwang-Soo
Publicado em 2008

G2385R and I2020T Mutations Increase LRRK2 GTPase Activity

Por Ho, Dong Hwan, Jang, Jihoon, Joe, Eun-hye, Son, Ilhong, Seo, Hyemyung, Seol, Wongi
Publicado no Biomed Res Int (2016)

An elongation factor-associating domain is inserted into human cysteinyl-tRNA synthetase by alternative splicing

Por Kim, Jee Eun, Kim, Kyoung-Hee, Lee, Sang Won, Seol, Wongi, Shiba, Kiyotaka, Kim, Sunghoon
Publicado em 2000

Oxidized DJ-1 Levels in Urine Samples as a Putative Biomarker for Parkinson's Disease

Por Jang, Jihoon, Jeong, Soyeon, Lee, Sung Ik, Seol, Wongi, Seo, Hyemyung, Son, Ilhong, Ho, Dong Hwan
Publicado no Parkinsons Dis (2018)

Genetic dissection of protein–protein interactions in multi-tRNA synthetase complex

Por Rho, Seung Bae, Kim, Min Jung, Lee, Jong Sang, Seol, Wongi, Motegi, Hiromi, Kim, Sunghoon, Shiba, Kiyotaka
Publicado em 1999

Activation of the orphan receptor RIP14 by retinoids

Por Zavacki, Ann Marie, Lehmann, Jürgen M., Seol, Wongi, Willson, Timothy M., Kliewer, Steven A., Moore, David D.
Publicado em 1997

Characterization of Parkinson’s disease-related pathogenic TMEM230 mutants

Por Nam, Daleum, Kim, Hyejung, Choi, Dong-Joo, Bae, Yun-Hee, Lee, Byoung Dae, Son, Ilhong, Seol, Wongi
Publicado no Anim Cells Syst (Seoul) (2018)

LRRK2 Kinase Activity Induces Mitochondrial Fission in Microglia via Drp1 and Modulates Neuroinflammation

Por Ho, Dong Hwan, Je, A Reum, Lee, Haejin, Son, Ilhong, Kweon, Hee-Seok, Kim, Hyung-Gun, Seol, Wongi
Publicado no Exp Neurobiol (2018)

Leucine-Rich Repeat Kinase 2 (LRRK2) Stimulates IL-1β-Mediated Inflammatory Signaling through Phosphorylation of RCAN1

Por Han, Kyung A., Yoo, Lang, Sung, Jee Y., Chung, Sun A., Um, Ji W., Kim, Hyeyoung, Seol, Wongi, Chung, Kwang C.
Publicado no Front Cell Neurosci (2017)

Increase in anti-apoptotic molecules, nucleolin, and heat shock protein 70, against upregulated LRRK2 kinase activity

Por Jang, Jihoon, Oh, Hakjin, Nam, Daleum, Seol, Wongi, Seo, Mi Kyoung, Park, Sung Woo, Kim, Hyung Gun, Seo, Hyemyung, Son, Ilhong, Ho, Dong Hwan
Publicado no Anim Cells Syst (Seoul) (2018)

Impaired Inflammatory Responses in Murine Lrrk2-Knockdown Brain Microglia

Por Kim, Beomsue, Yang, Myung-Soon, Choi, Dongjoo, Kim, Jong-Hyeon, Kim, Hye-Sun, Seol, Wongi, Choi, Sangdun, Jou, Ilo, Kim, Eun-Young, Joe, Eun-hye
Publicado em 2012

LRRK2 phosphorylates Snapin and inhibits interaction of Snapin with SNAP-25

Por Yun, Hye Jin, Park, Joohyun, Ho, Dong Hwan, Kim, Heyjung, Kim, Cy-Hyun, Oh, Hakjin, Ga, Inhwa, Seo, Hyemyung, Chang, Sunghoe, Son, Ilhong, Seol, Wongi
Publicado em 2013

Dexamethasone induces the expression of LRRK2 and α-synuclein, two genes that when mutated cause Parkinson’s disease in an autosomal dominant manner

Por Park, Ji-Min, Ho, Dong-Hwan, Yun, Hye Jin, Kim, Hye-Jung, Lee, Chan Hong, Park, Sung Woo, Kim, Young Hoon, Son, Ilhong, Seol, Wongi
Publicado em 2013

Leucine-Rich Repeat Kinase 2 (LRRK2) phosphorylates p53 and induces p21(WAF1/CIP1) expression

Por Ho, Dong Hwan, Kim, Hyejung, Kim, Jisun, Sim, Hyuna, Ahn, Hyunjun, Kim, Janghwan, Seo, Hyemyung, Chung, Kwang Chul, Park, Bum-Joon, Son, Ilhong, Seol, Wongi
Publicado no Mol Brain (2015)