Seeding Collaborations to Advance Kinase Science with the GSK Published Kinase Inhibitor Set (PKIS)

Autor Drewry, David H., Willson, Timothy M., Zuercher, William J.
Vydáno v Curr Top Med Chem (2014)

Gram-scale synthesis of FICZ, a photoreactive endogenous ligand of the aryl hydrocarbon receptor

Autor Zhang, Cunyu, Creech, Katrina L., Zuercher, William J., Willson, Timothy M.
Vydáno v Sci Rep (2019)

Chemical Approaches to Nuclear Receptors in Metabolism

Autor Margolis, Ronald N., Moore, David D., Willson, Timothy M., Guy, R. Kip
Vydáno v Sci Signal (2009)

A Perspective on Extreme Open Science: Companies Sharing Compounds without Restriction

Autor Drewry, David H., Wells, Carrow I., Zuercher, William J., Willson, Timothy M.
Vydáno v SLAS Discov (2019)

Concise, gram-scale synthesis of furo[2,3-b]pyridines with functional handles for chemoselective cross-coupling.

Autor O’Byrne, Sean N., Eduful, Benjamin J., Willson, Timothy M., Drewry, David H.
Vydáno v Tetrahedron Lett (2020)

The first completed genome sequence from a teleost fish (Fugu rubripes) adds significant diversity to the nuclear receptor superfamily

Autor Maglich, Jodi M., Caravella, Justin A., Lambert, Millard H., Willson, Timothy M., Moore, John T., Ramamurthy, Lakshman
Vydáno 2003

Crystal Structure of the PXR-T1317 Complex Provides a Scaffold to Examine the Potential for Receptor Antagonism

Autor Xue, Yu, Chao, Esther, Zuercher, William J., Willson, Timothy M., Collins, Jon L., Redinbo, Matthew R.
Vydáno 2006

Activation of the orphan receptor RIP14 by retinoids

Autor Zavacki, Ann Marie, Lehmann, Jürgen M., Seol, Wongi, Willson, Timothy M., Kliewer, Steven A., Moore, David D.
Vydáno 1997

Peroxisome proliferator–activated receptor γ ligands inhibit development of atherosclerosis in LDL receptor–deficient mice

Autor Li, Andrew C., Brown, Kathleen K., Silvestre, Mercedes J., Willson, Timothy M., Palinski, Wulf, Glass, Christopher K.
Vydáno 2000

Identification of Novel Pathways That Control Farnesoid X Receptor-mediated Hypocholesterolemia

Autor Zhang, Yanqiao, Yin, Liya, Anderson, Jody, Ma, Huiyan, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Vydáno 2010

Nonsteroidal Anti-Inflammatory Drugs and Peroxisome Proliferator-Activated Receptor-γ Agonists Modulate Immunostimulated Processing of Amyloid Precursor Protein through Regulation...

Autor Sastre, Magdalena, Dewachter, Ilse, Landreth, Gary E., Willson, Timothy M., Klockgether, Thomas, van Leuven, Fred, Heneka, Michael T.
Vydáno v J Neurosci (2003)

IL-4 inhibits osteoclast formation through a direct action on osteoclast precursors via peroxisome proliferator-activated receptor γ1

Autor Bendixen, Amy C., Shevde, Nirupama K., Dienger, Krista M., Willson, Timothy M., Funk, Colin D., Pike, J. Wesley
Vydáno 2001

Activation of the nuclear receptor FXR improves hyperglycemia and hyperlipidemia in diabetic mice

Autor Zhang, Yanqiao, Lee, Florence Ying, Barrera, Gabriel, Lee, Hans, Vales, Charisse, Gonzalez, Frank J., Willson, Timothy M., Edwards, Peter A.
Vydáno 2006

Parallel SUMOylation-dependent pathways mediate gene- and signal-specific transrepression by LXRs and PPARγ

Autor Ghisletti, Serena, Huang, Wendy, Ogawa, Sumito, Pascual, Gabriel, Lin, Mu-En, Willson, Timothy M., Rosenfeld, Michael G., Glass, Christopher K.
Vydáno 2007

Ligand Activation of Peroxisome Proliferator-Activated Receptor-β/δ (PPARβ/δ) Inhibits Cell Growth of Human N/TERT-1 Keratinocytes

Autor Burdick, Andrew D., Bility, Moses T., Girroir, Elizabeth E., Billin, Andrew N., Willson, Timothy M., Gonzalez, Frank J., Peters, Jeffrey M.
Vydáno 2007

Prostacyclin-mediated activation of peroxisome proliferator-activated receptor δ in colorectal cancer

Autor Gupta, Rajnish A., Tan, Jian, Krause, Wade F., Geraci, Mark W., Willson, Timothy M., Dey, Sudhansu K., DuBois, Raymond N.
Vydáno 2000

Comparison of complete nuclear receptor sets from the human, Caenorhabditis elegans and Drosophila genomes

Autor Maglich, Jodi M, Sluder, Ann, Guan, Xiaojun, Shi, Yunling, McKee, David D, Carrick, Kevin, Kamdar, Kim, Willson, Timothy M, Moore, John T
Vydáno 2001

The p300 Acetylase Is Critical for Ligand-activated Farnesoid X Receptor (FXR) Induction of SHP

Autor Fang, Sungsoon, Tsang, Stephanie, Jones, Ryan, Ponugoti, Bhaskar, Yoon, Hyeryoung, Wu, Shwu-Yuan, Chiang, Cheng-Ming, Willson, Timothy M., Kemper, Jongsook Kim
Vydáno 2008

Collaborative approaches for Target ID in neglected diseases: identifying new antimalarial targets

Autor Lafuente, Maria Jose, Guidelli-Disse, Sonja, Selenski, Carolyn, Lelievre, Joel, Willson, Timothy, Gamo, Francisco Javier, Drewes, Gerard, Vandal, Omar, Ballell-Pages, Luis
Vydáno 2014

Syndecan-1 expression is regulated in an isoform-specific manner by the farnesoid-X receptor. VOLUME 278 (2003) PAGES 20420-20428

Autor Anisfeld, Andrew M., Kast-Woelbern, Heidi R., Meyer, Marie E., Jones, Stacey A., Zhang, Yanqiao, Williams, Kevin J., Willson, Timothy, Edwards, Peter A.
Vydáno 2009