Insights Into Metabolic Mechanisms and Their Application in the Treatment of NASH

Por White, Phillip J., Abdelmalek, Manal F.
Publicado no Clin Liver Dis (Hoboken) (2021)

Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in Hig...

Por White, Phillip J., Arita, Makoto, Taguchi, Ryo, Kang, Jing X., Marette, André
Publicado em 2010

Endotoxin Mediated-iNOS Induction Causes Insulin Resistance via ONOO(−) Induced Tyrosine Nitration of IRS-1 in Skeletal Muscle

Por Pilon, Geneviève, Charbonneau, Alexandre, White, Phillip J., Dallaire, Patrice, Perreault, Mylène, Kapur, Sonia, Marette, André
Publicado em 2010

Protectin DX alleviates insulin resistance by activating a myokine-liver glucoregulatory axis

Por White, Phillip J., St-Pierre, Philippe, Charbonneau, Alexandre, Mitchell, Patricia, St-Amand, Emmanuelle, Marcotte, Bruno, Marette, André
Publicado no Nat Med (2014)

Focused Ultrasound Platform for Investigating Therapeutic Neuromodulation Across the Human Hippocampus

Por Brinker, Spencer T, Preiswerk, Frank, White, Phillip J, Mariano, Timothy Y, McDannold, Nathan J, Bubrick, Ellen J
Publicado no Ultrasound Med Biol (2020)

Lowering circulating apolipoprotein E levels improves aged bone fracture healing

Por Huang, Rong, Zong, Xiaohua, Nadesan, Puviindran, Huebner, Janet L., Kraus, Virginia B., White, James P., White, Phillip J., Baht, Gurpreet S.
Publicado no JCI Insight (2019)

Dietary branched-chain amino acid restriction alters fuel selection and reduces triglyceride stores in hearts of Zucker fatty rats

Por McGarrah, Robert W., Zhang, Guo-Fang, Christopher, Bridgette A., Deleye, Yann, Walejko, Jacquelyn M., Page, Stephani, Ilkayeva, Olga, White, Phillip J., Newgard, Christopher B.
Publicado no Am J Physiol Endocrinol Metab (2020)

MiR-29 Regulates de novo Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner

Por Hung, Yu-Han, Kanke, Matt, Kurtz, Catherine Lisa, Cubitt, Rebecca L., Bunaciu, Rodica P., Zhou, Liye, White, Phillip J., Vickers, Kasey C., Hussain, Mohammed Mahmood, Li, Xiaoling, Sethupathy, Praveen
Publicado no Front Physiol (2019)

High Resolution Melt (HRM) analysis is an efficient tool to genotype EMS mutants in complex crop genomes

Por Lochlainn, Seosamh Ó, Amoah, Stephen, Graham, Neil S, Alamer, Khalid, Rios, Juan J, Kurup, Smita, Stoute, Andrew, Hammond, John P, Østergaard, Lars, King, Graham J, White, Phillip J, Broadley, Martin R
Publicado em 2011

Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

Por Hung, Yu-Han, Kanke, Matt, Kurtz, C. Lisa, Cubitt, Rebecca, Bunaciu, Rodica P., Miao, Ji, Zhou, Liye, Graham, James L., Hussain, M. Mahmood, Havel, Peter, Biddinger, Sudha, White, Phillip J., Sethupathy, Praveen
Publicado no Physiol Genomics (2019)

Loss of BCAA catabolism during carcinogenesis enhances mTORCl activity and promotes tumor development and progression

Por Ericksen, Russell E., Lim, Siew Lan, McDonnell, Eoin, Shuen, Wai Ho, Vadiveloo, Maya, White, Phillip J., Ding, Zhaobing, Kwok, Royston, Lee, Philip, Radda, George K., Toh, Han Chong, Hirschey, Matthew D., Han, Weiping
Publicado no Cell Metab (2019)

Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

Por White, Phillip J., Lapworth, Amanda L., An, Jie, Wang, Liping, McGarrah, Robert W., Stevens, Robert D., Ilkayeva, Olga, George, Tabitha, Muehlbauer, Michael J., Bain, James R., Trimmer, Jeff K., Brosnan, M. Julia, Rolph, Timothy P., Newgard, Christopher B.
Publicado no Mol Metab (2016)

Brain insulin lowers circulating BCAA levels by inducing hepatic BCAA catabolism

Por Shin, Andrew C., Fasshauer, Martin, Filatova, Nika, Grundell, Linus A., Zielinski, Elizabeth, Zhou, Jian-Ying, Scherer, Thomas, Lindtner, Claudia, White, Phillip J., Lapworth, Amanda L., Ilkayeva, Olga, Knippschild, Uwe, Wolf, Anna M., Scheja, Ludger, Grove, Kevin L., Smith, Richard D., Qian, Wei-Jun, Lynch, Christopher J., Newgard, Christopher B., Buettner, Christoph
Publicado no Cell Metab (2014)

The BCKDH kinase and phosphatase integrate BCAA and lipid metabolism via regulation of ATP-citrate lyase

Por White, Phillip J., McGarrah, Robert W., Grimsrud, Paul A., Tso, Shih-Chia, Yang, Wen-Hsuan, Haldeman, Jonathan, Grenier-Larouche, Thomas, An, Jie, Lapworth, Amanda L, Astapova, Inna, Hannou, Sarah A., George, Tabitha, Arlotto, Michelle, Olson, Lyra B., Lai, Michelle, Zhang, Guofang, Ilkayeva, Olga, Herman, Mark A., Wynn, R. Max, Chuang, David T., Newgard, Christopher B.
Publicado no Cell Metab (2018)

Impact of combined resistance and aerobic exercise training on branched-chain amino acid turnover, glycine metabolism and insulin sensitivity in overweight humans

Por Glynn, Erin L., Piner, Lucy W., Huffman, Kim M., Slentz, Cris A., Elliot-Penry, Lorraine, AbouAssi, Hiba, White, Phillip J., Bain, James R., Muehlbauer, Michael J., Ilkayeva, Olga R., Stevens, Robert D., Porter Starr, Kathryn N., Bales, Connie W., Volpi, Elena, Brosnan, M. Julia, Trimmer, Jeff K., Rolph, Timothy P., Newgard, Christopher B., Kraus, William E.
Publicado no Diabetologia (2015)

Branched-chain α-ketoacids are preferentially reaminated and activate protein synthesis in the heart

Por Walejko, Jacquelyn M., Christopher, Bridgette A., Crown, Scott B., Zhang, Guo-Fang, Pickar-Oliver, Adrian, Yoneshiro, Takeshi, Foster, Matthew W., Page, Stephani, van Vliet, Stephan, Ilkayeva, Olga, Muehlbauer, Michael J., Carson, Matthew W., Brozinick, Joseph T., Hammond, Craig D., Gimeno, Ruth E., Moseley, M. Arthur, Kajimura, Shingo, Gersbach, Charles A., Newgard, Christopher B., White, Phillip J., McGarrah, Robert W.
Publicado no Nat Commun (2021)

BCAA catabolism in brown fat controls energy homeostasis through SLC25A44

Por Yoneshiro, Takeshi, Wang, Qiang, Tajima, Kazuki, Matsushita, Mami, Maki, Hiroko, Igarashi, Kaori, Dai, Zhipeng, White, Phillip J., McGarrah, Robert W., Ilkayeva, Olga R, Deleye, Yann, Oguri, Yasuo, Kuroda, Mito, Ikeda, Kenji, Li, Huixia, Ueno, Ayano, Ohishi, Maki, Ishikawa, Takamasa, Kim, Kyeongkyu, Chen, Yong, Sponton, Carlos Henrique, Pradhan, Rachana N., Majd, Homa, Greiner, Vanille Juliette, Yoneshiro, Momoko, Brown, Zachary, Chondronikola, Maria, Takahashi, Haruya, Goto, Tsuyoshi, Kawada, Teruo, Sidossis, Labros, Szoka, Francis C., McManus, Michael T., Saito, Masayuki, Soga, Tomoyoshi, Kajimura, Shingo
Publicado no Nature (2019)