Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

MicroRNAs (miRNAs) are important posttranscriptional regulators of metabolism and energy homeostasis. Dysregulation of certain miRNAs in the liver has been shown to contribute to the pathogenesis of Type 2 diabetes (T2D), in part by impairing hepatic insulin sensitivity. By small RNA-sequencing anal...

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Detalhes bibliográficos
Publicado no:Physiol Genomics
Main Authors: Hung, Yu-Han, Kanke, Matt, Kurtz, C. Lisa, Cubitt, Rebecca, Bunaciu, Rodica P., Miao, Ji, Zhou, Liye, Graham, James L., Hussain, M. Mahmood, Havel, Peter, Biddinger, Sudha, White, Phillip J., Sethupathy, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: American Physiological Society 2019
Assuntos:
Research Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732414/
https://ncbi.nlm.nih.gov/pubmed/31251698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00037.2019
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