Acute suppression of insulin resistance-associated hepatic miR-29 in vivo improves glycemic control in adult mice

MicroRNAs (miRNAs) are important posttranscriptional regulators of metabolism and energy homeostasis. Dysregulation of certain miRNAs in the liver has been shown to contribute to the pathogenesis of Type 2 diabetes (T2D), in part by impairing hepatic insulin sensitivity. By small RNA-sequencing anal...

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Publicado en:Physiol Genomics
Autores principales: Hung, Yu-Han, Kanke, Matt, Kurtz, C. Lisa, Cubitt, Rebecca, Bunaciu, Rodica P., Miao, Ji, Zhou, Liye, Graham, James L., Hussain, M. Mahmood, Havel, Peter, Biddinger, Sudha, White, Phillip J., Sethupathy, Praveen
Formato: Artigo
Lenguaje:Inglês
Publicado: American Physiological Society 2019
Materias:
Research Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC6732414/
https://ncbi.nlm.nih.gov/pubmed/31251698
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1152/physiolgenomics.00037.2019
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