MiR-29 Regulates de novo Lipogenesis in the Liver and Circulating Triglyceride Levels in a Sirt1-Dependent Manner

MicroRNAs (miRNAs) are known regulators of lipid homeostasis. We recently demonstrated that miR-29 controls the levels of circulating cholesterol and triglycerides, but the mechanisms remained unknown. In the present study, we demonstrated that systemic delivery of locked nucleic acid inhibitor of m...

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Detalhes bibliográficos
Publicado no:Front Physiol
Main Authors: Hung, Yu-Han, Kanke, Matt, Kurtz, Catherine Lisa, Cubitt, Rebecca L., Bunaciu, Rodica P., Zhou, Liye, White, Phillip J., Vickers, Kasey C., Hussain, Mohammed Mahmood, Li, Xiaoling, Sethupathy, Praveen
Formato: Artigo
Idioma:Inglês
Publicado em: Frontiers Media S.A. 2019
Assuntos:
Physiology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC6828850/
https://ncbi.nlm.nih.gov/pubmed/31736786
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.3389/fphys.2019.01367
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