Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

OBJECTIVE: A branched-chain amino acid (BCAA)-related metabolic signature is strongly associated with insulin resistance and predictive of incident diabetes and intervention outcomes. To better understand the role that this metabolite cluster plays in obesity-related metabolic dysfunction, we studie...

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Detalhes bibliográficos
Publicado no:Mol Metab
Main Authors: White, Phillip J., Lapworth, Amanda L., An, Jie, Wang, Liping, McGarrah, Robert W., Stevens, Robert D., Ilkayeva, Olga, George, Tabitha, Muehlbauer, Michael J., Bain, James R., Trimmer, Jeff K., Brosnan, M. Julia, Rolph, Timothy P., Newgard, Christopher B.
Formato: Artigo
Idioma:Inglês
Publicado em: Elsevier 2016
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Original Article
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921791/
https://ncbi.nlm.nih.gov/pubmed/27408778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.006
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