Branched-chain amino acid restriction in Zucker-fatty rats improves muscle insulin sensitivity by enhancing efficiency of fatty acid oxidation and acyl-glycine export

OBJECTIVE: A branched-chain amino acid (BCAA)-related metabolic signature is strongly associated with insulin resistance and predictive of incident diabetes and intervention outcomes. To better understand the role that this metabolite cluster plays in obesity-related metabolic dysfunction, we studie...

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Detaylı Bibliyografya
Yayımlandı:Mol Metab
Asıl Yazarlar: White, Phillip J., Lapworth, Amanda L., An, Jie, Wang, Liping, McGarrah, Robert W., Stevens, Robert D., Ilkayeva, Olga, George, Tabitha, Muehlbauer, Michael J., Bain, James R., Trimmer, Jeff K., Brosnan, M. Julia, Rolph, Timothy P., Newgard, Christopher B.
Materyal Türü: Artigo
Dil:Inglês
Baskı/Yayın Bilgisi: Elsevier 2016
Konular:
Original Article
Online Erişim:https://ncbi.nlm.nih.gov/pmc/articles/PMC4921791/
https://ncbi.nlm.nih.gov/pubmed/27408778
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.molmet.2016.04.006
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