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Transgenic Restoration of Long-Chain n-3 Fatty Acids in Insulin Target Tissues Improves Resolution Capacity and Alleviates Obesity-Linked Inflammation and Insulin Resistance in High-Fat–Fed Mice

OBJECTIVE: The catabasis of inflammation is an active process directed by n-3 derived pro-resolving lipid mediators. We aimed to determine whether high-fat (HF) diet-induced n-3 deficiency compromises the resolution capacity of obese mice and thereby contributes to obesity-linked inflammation and in...

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Detalhes bibliográficos
Main Authors: White, Phillip J., Arita, Makoto, Taguchi, Ryo, Kang, Jing X., Marette, André
Formato: Artigo
Idioma:Inglês
Publicado em: American Diabetes Association 2010
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2992767/
https://ncbi.nlm.nih.gov/pubmed/20841610
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.2337/db10-0054
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