Particle Based Technologies for Osteoarthritis Detection and Therapy

Por Kavanaugh, Taylor E., Werfel, Thomas A., Cho, Hongsik, Hasty, Karen A., Duvall, Craig L.
Publicado no Drug Deliv Transl Res (2016)

Future nanomedicine for the diagnosis and treatment of osteoarthritis

Por Eichaker, Lauren R, Cho, Hongsik, Duvall, Craig L, Werfel, Thomas A, Hasty, Karen A
Publicado no Nanomedicine (Lond) (2014)

Combinatorial Optimization of PEG Architecture and Hydrophobic Content Improves siRNA Polyplex Stability, Pharmacokinetics, and Potency In Vivo

Por Werfel, Thomas A., Jackson, Meredith A., Kavanaugh, Taylor E., Kirkbride, Kellye C., Miteva, Martina, Giorgio, Todd D., Duvall, Craig
Publicado no J Control Release (2017)

Hydrolytic charge-reversal of PEGylated polyplexes enhances intracellular un-packaging and activity of siRNA

Por Werfel, Thomas A., Swain, Corban, Nelson, Christopher E., Kilchrist, Kameron V., Evans, Brian C., Miteva, Martina, Duvall, Craig L.
Publicado no J Biomed Mater Res A (2016)

Enhanced Performance of Plasmid DNA Polyplexes Stabilized by a Combination of Core Hydrophobicity and Surface PEGylation

Por Adolph, Elizabeth J., Nelson, Christopher E., Werfel, Thomas A., Guo, Ruijing, Davidson, Jeffrey M., Guelcher, Scott A., Duvall, Craig L.
Publicado no J Mater Chem B Mater Biol Med (2014)

Lipophilic siRNA targets albumin in situ and promotes bioavailability, tumor penetration, and carrier-free gene silencing

Por Sarett, Samantha M., Werfel, Thomas A., Lee, Linus, Jackson, Meredith A., Kilchrist, Kameron V., Brantley-Sieders, Dana, Duvall, Craig L.
Publicado no Proc Natl Acad Sci U S A (2017)

Hydrophobic Interactions between Polymeric Carrier and Palmitic Acid-Conjugated siRNA Improve PEGylated Polyplex Stability and Enhance In Vivo Pharmacokinetics and Tumor Gene Silen...

Por Sarett, Samantha, Werfel, Thomas A, Chandra, Irene, Jackson, Meredith A, Kavanaugh, Taylor E, Hattaway, Madison E, Giorgio, Todd D, Duvall, Craig L
Publicado no Biomaterials (2016)

Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers

Por Miteva, Martina, Kirkbride, Kellye C., Kilchrist, Kameron V., Werfel, Thomas A., Li, Hongmei, Nelson, Christopher E., Gupta, Mukesh K., Giorgio, Todd D., Duvall, Craig L.
Publicado no Biomaterials (2014)

Fluorocoxib A Loaded Nanoparticles Enable Targeted Visualization of Cyclooxygenase-2 in Inflammation and Cancer

Por Uddin, Md. Jashim, Werfel, Thomas A., Crews, Brenda C., Gupta, Mukesh K., Kavanaugh, Taylor E., Kingsley, Philip J., Boyd, Kelli, Marnett, Lawrence J., Duvall, Craig L.
Publicado no Biomaterials (2016)

Porous Silicon and Polymer Nanocomposites for Delivery of Peptide Nucleic Acids as anti-microRNA Therapies

Por Beavers, Kelsey R., Werfel, Thomas A., Shen, Tianwei, Kavanaugh, Taylor E., Kilchrist, Kameron V., Mares, Jeremy W., Fain, Joshua S., Wiese, Carrie B., Vickers, Kasey C., Weiss, Sharon M., Duvall, Craig L.
Publicado no Adv Mater (2016)

Zwitterionic Nanocarrier Surface Chemistry Improves siRNA Tumor Delivery and Silencing Activity Relative to Polyethylene Glycol

Por Jackson, Meredith A, Werfel, Thomas A., Curvino, Elizabeth J., Yu, Fang, Kavanaugh, Taylor E., Sarett, Samantha M., Dockery, Mary D., Kilchrist, Kameron V., Jackson, Ayisha N., Giorgio, Todd D., Duvall, Craig L.
Publicado no ACS Nano (2017)

Selective mTORC2 inhibitor therapeutically blocks breast cancer cell growth and survival

Por Werfel, Thomas A., Wang, Shan, Jackson, Meredith A., Kavanaugh, Taylor E., Joly, Meghan Morrison, Lee, Linus H., Hicks, Donna J., Sanchez, Violeta, Ericsson, Paula Gonzalez, Kilchrist, Kameron V., Dimobi, Somtochukwu C., Sarett, Samantha M., Brantley-Sieders, Dana, Cook, Rebecca S., Duvall, Craig L.
Publicado no Cancer Res (2018)