Tuning PEGylation of mixed micelles to overcome intracellular and systemic siRNA delivery barriers

A series of endosomolytic mixed micelles was synthesized from two diblock polymers, poly[ethylene glycol-b-(dimethylaminoethyl methacrylate-co-propylacrylic acid-co-butyl methacrylate)] (PEG-b-pDPB) and poly[dimethylaminoethyl methacrylate-b-(dimethylaminoethyl methacrylate-co-propylacrylic acid-co-...

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Publicado en:Biomaterials
Autores principales: Miteva, Martina, Kirkbride, Kellye C., Kilchrist, Kameron V., Werfel, Thomas A., Li, Hongmei, Nelson, Christopher E., Gupta, Mukesh K., Giorgio, Todd D., Duvall, Craig L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2014
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Article
Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC5477977/
https://ncbi.nlm.nih.gov/pubmed/25453977
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2014.10.036
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