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Matrix Metalloproteinase Responsive, Proximity-activated Polymeric Nanoparticles for siRNA Delivery

Small interfering RNA (siRNA) has significant potential to evolve into a new class of pharmaceutical inhibitors, but technologies that enable robust, tissue-specific intracellular delivery must be developed before effective clinical translation can be achieved. A pH-responsive, smart polymeric nanop...

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Detalhes bibliográficos
Main Authors: Li, Hongmei, Yu, Shann S., Miteva, Martina, Nelson, Christopher E., Werfel, Thomas, Giorgio, Todd D., Duvall, Craig L.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC4159188/
https://ncbi.nlm.nih.gov/pubmed/25214828
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adfm.201202215
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