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Technologies for Controlled, Local Delivery of siRNA

The discovery of RNAi in the late 1990s unlocked a new realm of therapeutic possibilities by enabling potent and specific silencing of theoretically any desired genetic target. Better elucidation of the mechanism of action, the impact of chemical modifications that stabilize and reduce nonspecific e...

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Bibliographic Details
Published in:J Control Release
Main Authors: Sarett, Samantha M., Nelson, Christopher E., Duvall, Craig L.
Format: Artigo
Language:Inglês
Published: 2015
Subjects:
Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665980/
https://ncbi.nlm.nih.gov/pubmed/26476177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.066
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