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Technologies for Controlled, Local Delivery of siRNA

The discovery of RNAi in the late 1990s unlocked a new realm of therapeutic possibilities by enabling potent and specific silencing of theoretically any desired genetic target. Better elucidation of the mechanism of action, the impact of chemical modifications that stabilize and reduce nonspecific e...

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Bibliografiska uppgifter
I publikationen:J Control Release
Huvudupphovsmän: Sarett, Samantha M., Nelson, Christopher E., Duvall, Craig L.
Materialtyp: Artigo
Språk:Inglês
Publicerad: 2015
Ämnen:
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665980/
https://ncbi.nlm.nih.gov/pubmed/26476177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.066
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