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Technologies for Controlled, Local Delivery of siRNA

The discovery of RNAi in the late 1990s unlocked a new realm of therapeutic possibilities by enabling potent and specific silencing of theoretically any desired genetic target. Better elucidation of the mechanism of action, the impact of chemical modifications that stabilize and reduce nonspecific e...

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Detalles Bibliográficos
Publicado en:J Control Release
Autores principales: Sarett, Samantha M., Nelson, Christopher E., Duvall, Craig L.
Formato: Artigo
Lenguaje:Inglês
Publicado: 2015
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Acceso en línea:https://ncbi.nlm.nih.gov/pmc/articles/PMC4665980/
https://ncbi.nlm.nih.gov/pubmed/26476177
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.066
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