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Technologies for Controlled, Local Delivery of siRNA
The discovery of RNAi in the late 1990s unlocked a new realm of therapeutic possibilities by enabling potent and specific silencing of theoretically any desired genetic target. Better elucidation of the mechanism of action, the impact of chemical modifications that stabilize and reduce nonspecific e...
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| Published in: | J Control Release |
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| Main Authors: | , , |
| Format: | Artigo |
| Language: | Inglês |
| Published: |
2015
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| Subjects: | |
| Online Access: | https://ncbi.nlm.nih.gov/pmc/articles/PMC4665980/ https://ncbi.nlm.nih.gov/pubmed/26476177 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.jconrel.2015.09.066 |
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