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Local delivery of PHD2 siRNA from ROS-degradable scaffolds to promote diabetic wound healing
siRNA delivered from ROS-degradable tissue engineering scaffolds promotes diabetic wound healing in rats. Porous poly(thioketal-urethane) (PTK-UR) scaffolds implanted in diabetic wounds locally deliver siRNA that inhibits the expression of prolyl hydroxylase domain protein 2 (PHD2), thereby increasi...
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| Veröffentlicht in: | Adv Healthc Mater |
|---|---|
| Hauptverfasser: | , , , , , , , , , , |
| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2016
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC5152672/ https://ncbi.nlm.nih.gov/pubmed/27717176 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/adhm.201600820 |
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