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Sustained Local Delivery of siRNA from an Injectable Scaffold
Controlled gene silencing technologies have significant, unrealized potential for use in tissue regeneration applications. The design described herein provides a means to package and protect siRNA within pH-responsive, endosomolytic micellar nanoparticles (si-NPs) that can be incorporated into nonto...
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| Hauptverfasser: | , , , , , |
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| Format: | Artigo |
| Sprache: | Inglês |
| Veröffentlicht: |
2011
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| Schlagworte: | |
| Online Zugang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC3232066/ https://ncbi.nlm.nih.gov/pubmed/22061489 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1016/j.biomaterials.2011.10.033 |
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