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Localized, Targeted, and Sustained siRNA Delivery

Short interfering RNA (siRNA) functions directly in the cytoplasm, where it is assembled into an RNA‐induced silencing complex (RISC). The localized delivery of siRNA to a specific site in vivo is highly challenging. There are many disease states in which a systemic effect of RNAi may be desirable;...

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Dades bibliogràfiques
Publicat a:Chemistry
Autors principals: Krebs, Melissa D., Alsberg, Eben
Format: Artigo
Idioma:Inglês
Publicat: WILEY‐VCH Verlag 2011
Matèries:
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC7162106/
https://ncbi.nlm.nih.gov/pubmed/21341332
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201003144
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