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Localized, Targeted, and Sustained siRNA Delivery
Short interfering RNA (siRNA) functions directly in the cytoplasm, where it is assembled into an RNA‐induced silencing complex (RISC). The localized delivery of siRNA to a specific site in vivo is highly challenging. There are many disease states in which a systemic effect of RNAi may be desirable;...
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| Опубликовано в: : | Chemistry |
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| Главные авторы: | , |
| Формат: | Artigo |
| Язык: | Inglês |
| Опубликовано: |
WILEY‐VCH Verlag
2011
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| Предметы: | |
| Online-ссылка: | https://ncbi.nlm.nih.gov/pmc/articles/PMC7162106/ https://ncbi.nlm.nih.gov/pubmed/21341332 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/chem.201003144 |
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