Optimizing Mannose “Click” Conjugation to Polymeric Nanoparticles for Targeted siRNA Delivery to Human and Murine Macrophages

[Image: see text] “Smart”, dual pH-responsive, and endosomolytic polymeric nanoparticles have demonstrated great potential for localized drug delivery, especially for siRNA delivery to the cytoplasm of cells. However, targeted delivery to a specific cell phenotype requires an additional level of fun...

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Publicat a:ACS Omega
Autors principals: Glass, Evan B., Masjedi, Shirin, Dudzinski, Stephanie O., Wilson, Andrew J., Duvall, Craig L., Yull, Fiona E., Giorgio, Todd D.
Format: Artigo
Idioma:Inglês
Publicat: American Chemical Society 2019
Accés en línia:https://ncbi.nlm.nih.gov/pmc/articles/PMC6796989/
https://ncbi.nlm.nih.gov/pubmed/31646220
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/acsomega.9b01465
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