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Macrophage-Specific RNAi Targeting via ‘Click’, Mannosylated Polymeric Micelles

Macrophages represent an important therapeutic target, because their activity has been implicated in the progression of debilitating diseases such as cancer and atherosclerosis. In this work, we designed and characterized pH-responsive polymeric micelles that were mannosylated using ‘click’ chemistr...

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Detalhes bibliográficos
Main Authors: Yu, Shann S., Lau, Cheryl M., Barham, Whitney J., Onishko, Halina M., Nelson, Christopher E., Li, Hongmei, Smith, Chelsey A., Yull, Fiona E., Duvall, Craig L., Giorgio, Todd D.
Formato: Artigo
Idioma:Inglês
Publicado em: 2013
Assuntos:
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC3595119/
https://ncbi.nlm.nih.gov/pubmed/23331322
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1021/mp300434e
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