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Aberrant activation of NF-κB signaling in mammary epithelium leads to abnormal growth and ductal carcinoma in situ

BACKGROUND: Approximately 1 in 5 women diagnosed with breast cancer are considered to have in situ disease, most often termed ductal carcinoma in situ (DCIS). Though recognized as a risk factor for the development of more invasive cancer, it remains unclear what factors contribute to DCIS developmen...

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Bibliographic Details
Published in:BMC Cancer
Main Authors: Barham, Whitney, Chen, Lianyi, Tikhomirov, Oleg, Onishko, Halina, Gleaves, Linda, Stricker, Thomas P., Blackwell, Timothy S., Yull, Fiona E.
Format: Artigo
Language:Inglês
Published: BioMed Central 2015
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Online Access:https://ncbi.nlm.nih.gov/pmc/articles/PMC4590702/
https://ncbi.nlm.nih.gov/pubmed/26424146
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1186/s12885-015-1652-8
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