PDUFA VI: It Is Time to Unleash the Full Potential of Model‐Informed Drug Development

av Jain, Lokesh, Mehrotra, Nitin, Wenning, Larissa, Sinha, Vikram
I publikationen CPT Pharmacometrics Syst Pharmacol (2018)

Exposure–response characterisation of tildrakizumab in chronic plaque psoriasis: Pooled analysis of 3 randomised controlled trials

av Kerbusch, Thomas, Li, Hanbin, Wada, Russell, Jauslin, Petra M., Wenning, Larissa
I publikationen Br J Clin Pharmacol (2020)

Population Pharmacokinetics of Doravirine and Exposure-Response Analysis in Individuals with HIV-1

av Yee, Ka Lai, Ouerdani, Aziz, Claussen, Anetta, de Greef, Rik, Wenning, Larissa
I publikationen Antimicrob Agents Chemother (2019)

Raltegravir In Vitro Effect on Bilirubin Binding

av Clarke, Diana F., Wong, Ronald J, Wenning, Larissa, Stevenson, David K., Mirochnick, Mark
Publicerad 2013

Clinical Pharmacokinetics of the Novel HIV-1 Non-Nucleoside Reverse Transcriptase Inhibitor Doravirine: An Assessment of the Effect of Patient Characteristics and Drug–Drug Interac...

av Khalilieh, Sauzanne, Yee, Ka Lai, Sanchez, Rosa, Stoch, S. Aubrey, Wenning, Larissa, Iwamoto, Marian
I publikationen Clin Drug Investig (2020)

Leveraging model-informed approaches for drug discovery and development in the cardiovascular space

av Dockendorf, Marissa F., Vargo, Ryan C., Gheyas, Ferdous, Chain, Anne S. Y., Chatterjee, Manash S., Wenning, Larissa A.
I publikationen J Pharmacokinet Pharmacodyn (2018)

Maternal–Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

av Lommerse, Jos, Clarke, Diana, Kerbusch, Thomas, Merdjan, Henri, Witjes, Han, Teppler, Hedy, Mirochnick, Mark, Acosta, Edward P., Wenning, Larissa, Nachman, Sharon, Chain, Anne
I publikationen CPT Pharmacometrics Syst Pharmacol (2019)

Pharmacokinetics and Pharmacodynamics of Once-Daily versus Twice-Daily Raltegravir in Treatment-Naïve HIV-Infected Patients

av Rizk, Matthew L., Hang, Yaming, Luo, Wen-Lin, Su, Jing, Zhao, Jing, Campbell, Havilland, Nguyen, Bach-Yen T., Sklar, Peter, Eron, Joseph J., Wenning, Larissa
Publicerad 2012

Effect of Tipranavir-Ritonavir on Pharmacokinetics of Raltegravir

av Hanley, William D., Wenning, Larissa A., Moreau, Allison, Kost, James T., Mangin, Eric, Shamp, Trisha, Stone, Julie A., Gottesdiener, Keith M., Wagner, John A., Iwamoto, Marian
Publicerad 2009

Effect of raltegravir on estradiol and norgestimate plasma pharmacokinetics following oral contraceptive administration in healthy women

av Anderson, Matt S, Hanley, William D, Moreau, Allison R, Jin, Bo, Bieberdorf, Frederick A, Kost, James T, Wenning, Larissa A, Stone, Julie A, Wagner, John A, Iwamoto, Marian
Publicerad 2011

Minimal Pharmacokinetic Interaction between the Human Immunodeficiency Virus Nonnucleoside Reverse Transcriptase Inhibitor Etravirine and the Integrase Inhibitor Raltegravir in Hea...

av Anderson, Matt S., Kakuda, Thomas N., Hanley, William, Miller, Jutta, Kost, James T., Stoltz, Randall, Wenning, Larissa A., Stone, Julie A., Hoetelmans, Richard M. W., Wagner, John A., Iwamoto, Marian
Publicerad 2008

Population Pharmacokinetic Analysis of Raltegravir Pediatric Formulations in HIV-infected Children 4 weeks to 18 years of age

av Rizk, Matthew L., Du, Lihong, Bennetto-Hood, Chantelle, Wenning, Larissa, Teppler, Hedy, Homony, Brenda, Graham, Bobbie, Fry, Carrie, Nachman, Sharon, Wiznia, Andrew, Worrell, Carol, Smith, Betsy, Acosta, Edward P.
I publikationen J Clin Pharmacol (2015)

Population Pharmacokinetic Modeling to Evaluate Standard Magnesium Sulfate Treatments and Alternative Dosing Regimens for Women With Preeclampsia

av Du, Lihong, Wenning, Larissa, Migoya, Elizabeth, Xu, Yan, Carvalho, Brendan, Brookfield, Kathleen, Witjes, Han, de Greef, Rik, Lumbiganon, Pisake, Sangkomkamhang, Ussanee, Titapant, Vitaya, Duley, Lelia, Long, Qian, Oladapo, Olufemi T.
I publikationen J Clin Pharmacol (2018)

Lack of a Significant Drug Interaction between Raltegravir and Tenofovir

av Wenning, Larissa A., Friedman, Evan J., Kost, James T., Breidinger, Sheila A., Stek, Jon E., Lasseter, Kenneth C., Gottesdiener, Keith M., Chen, Joshua, Teppler, Hedy, Wagner, John A., Stone, Julie A., Iwamoto, Marian
Publicerad 2008

Lack of a Clinically Important Effect of Moderate Hepatic Insufficiency and Severe Renal Insufficiency on Raltegravir Pharmacokinetics

av Iwamoto, Marian, Hanley, William D., Petry, Amelia S., Friedman, Evan J., Kost, James T., Breidinger, Sheila A., Lasseter, Kenneth C., Robson, Richard, Lunde, Norman M., Wenning, Larissa A., Stone, Julie A., Wagner, John A.
Publicerad 2009

Alternative Magnesium Sulfate Dosing Regimens for Women With Preeclampsia: A Population Pharmacokinetic Exposure‐Response Modeling and Simulation Study

av Du, Lihong, Wenning, Larissa A., Carvalho, Brendan, Duley, Lelia, Brookfield, Kathleen F., Witjes, Han, de Greef, Rik, Lumbiganon, Pisake, Titapant, Vitaya, Kongwattanakul, Kiattisak, Long, Qian, Sangkomkamhang, Ussanee S., Gülmezoglu, Ahmet M., Oladapo, Olufemi T.
I publikationen J Clin Pharmacol (2019)

Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir

av Iwamoto, Marian, Wenning, Larissa A., Petry, Amelia S., Laethem, Martine, De Smet, Marina, Kost, James T., Breidinger, Sheila A., Mangin, Eric C., Azrolan, Neal, Greenberg, Howard E., Haazen, Wouter, Stone, Julie A., Gottesdiener, Keith M., Wagner, John A.
Publicerad 2008

Effect of Rifampin, a Potent Inducer of Drug-Metabolizing Enzymes, on the Pharmacokinetics of Raltegravir

av Wenning, Larissa A., Hanley, William D., Brainard, Diana M., Petry, Amelia S., Ghosh, Kalyan, Jin, Bo, Mangin, Eric, Marbury, Thomas C., Berg, Jolene K., Chodakewitz, Jeffrey A., Stone, Julie A., Gottesdiener, Keith M., Wagner, John A., Iwamoto, Marian
Publicerad 2009

Pharmacokinetic–pharmacodynamic studies of the 11β-hydroxysteroid dehydrogenase type 1 inhibitor MK-0916 in healthy subjects

av Wright, D Hamish, Stone, Julie A, Crumley, Tami M, Wenning, Larissa, Zheng, Wei, Yan, Kerri, Yang, Amy Yifan, Sun, Li, Cilissen, Caroline, Ramael, Steven, Hermanowski-Vosatka, Anne, Langdon, Ronald B, Gottesdiener, Keith M, Wagner, John A, Lai, Eseng
Publicerad 2013

Effect of Hepatic Impairment on the Pharmacokinetics of Grazoprevir, a Hepatitis C Virus Protease Inhibitor

av Caro, Luzelena, Wenning, Larissa, Guo, Zifang, Fraser, Iain P., Fandozzi, Christine, Talaty, Jennifer, Panebianco, Deborah, Ho, Maureen, Uemura, Naoto, Reitmann, Christina, Angus, Peter, Gane, Edward, Marbury, Thomas, Smith, William B., Iwamoto, Marian, Butterton, Joan R., Yeh, Wendy W.
I publikationen Antimicrob Agents Chemother (2017)