Maternal–Neonatal Raltegravir Population Pharmacokinetics Modeling: Implications for Initial Neonatal Dosing

Raltegravir readily crosses the placenta to the fetus with maternal use during pregnancy. After birth, neonatal raltegravir elimination is highly variable and often extremely prolonged, with some neonates demonstrating rising profiles after birth despite removal from the source of extrinsic raltegra...

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Udgivet i:CPT Pharmacometrics Syst Pharmacol
Main Authors: Lommerse, Jos, Clarke, Diana, Kerbusch, Thomas, Merdjan, Henri, Witjes, Han, Teppler, Hedy, Mirochnick, Mark, Acosta, Edward P., Wenning, Larissa, Nachman, Sharon, Chain, Anne
Format: Artigo
Sprog:Inglês
Udgivet: John Wiley and Sons Inc. 2019
Fag:
Research
Online adgang:https://ncbi.nlm.nih.gov/pmc/articles/PMC6765695/
https://ncbi.nlm.nih.gov/pubmed/31215170
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/psp4.12443
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