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Use of Modeling and Simulations to Determine Raltegravir Dosing in Neonates: A Model for Safely and Efficiently Determining Appropriate Neonatal Dosing Regimens: IMPAACT P1110
BACKGROUND: Population modeling and simulations can be used to facilitate the conduct of Phase I studies to develop safe and effective dosing regimens in neonates. SETTING: P1110 is an international, multicenter trial to determine safe and effective raltegravir doses in neonates at risk for HIV infe...
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| Publié dans: | J Acquir Immune Defic Syndr |
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| Auteurs principaux: | , , , , , , , |
| Format: | Artigo |
| Langue: | Inglês |
| Publié: |
2019
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| Sujets: | |
| Accès en ligne: | https://ncbi.nlm.nih.gov/pmc/articles/PMC6820708/ https://ncbi.nlm.nih.gov/pubmed/31658182 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1097/QAI.0000000000002149 |
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