Population Pharmacokinetic Analysis of Raltegravir Pediatric Formulations in HIV-infected Children 4 weeks to 18 years of age

P1066 is an open-label study of raltegravir in HIV+ youth, ages 4 weeks-18 years. Here we summarize P1066 pharmacokinetic (PK) data and a population PK model for the pediatric chewable tablet and oral granules. Raltegravir PK parameters were calculated using non-compartmental analysis. A two-compart...

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Опубликовано в: :J Clin Pharmacol
Главные авторы: Rizk, Matthew L., Du, Lihong, Bennetto-Hood, Chantelle, Wenning, Larissa, Teppler, Hedy, Homony, Brenda, Graham, Bobbie, Fry, Carrie, Nachman, Sharon, Wiznia, Andrew, Worrell, Carol, Smith, Betsy, Acosta, Edward P.
Формат: Artigo
Язык:Inglês
Опубликовано: 2015
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Article
Online-ссылка:https://ncbi.nlm.nih.gov/pmc/articles/PMC4572519/
https://ncbi.nlm.nih.gov/pubmed/25753401
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1002/jcph.493
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