Effect of Tipranavir-Ritonavir on Pharmacokinetics of Raltegravir

Raltegravir (RAL) is a novel and potent human immunodeficiency virus type 1 integrase inhibitor that is predominantly metabolized via glucuronidation. The protease inhibitor combination tipranavir (TPV) at 500 mg and ritonavir (RTV) at 200 mg (TPV-RTV) has inhibitory and inductive effects on metabol...

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Detalhes bibliográficos
Main Authors: Hanley, William D., Wenning, Larissa A., Moreau, Allison, Kost, James T., Mangin, Eric, Shamp, Trisha, Stone, Julie A., Gottesdiener, Keith M., Wagner, John A., Iwamoto, Marian
Formato: Artigo
Idioma:Inglês
Publicado em: American Society for Microbiology (ASM) 2009
Assuntos:
Pharmacology
Acesso em linha:https://ncbi.nlm.nih.gov/pmc/articles/PMC2704640/
https://ncbi.nlm.nih.gov/pubmed/19398643
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01486-08
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