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Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir
Raltegravir is a novel human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor with potent in vitro activity against HIV-1 (95% inhibitory concentration = 31 nM in 50% human serum). The possible effects of ritonavir and efavirenz on raltegravir pharmacokinetics were separatel...
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| Main Authors: | , , , , , , , , , , , , , |
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| Format: | Artigo |
| Sprog: | Inglês |
| Udgivet: |
American Society for Microbiology (ASM)
2008
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| Fag: | |
| Online adgang: | https://ncbi.nlm.nih.gov/pmc/articles/PMC2592871/ https://ncbi.nlm.nih.gov/pubmed/18838589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01543-07 |
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