Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir

Raltegravir is a novel human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor with potent in vitro activity against HIV-1 (95% inhibitory concentration = 31 nM in 50% human serum). The possible effects of ritonavir and efavirenz on raltegravir pharmacokinetics were separatel...

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Bibliografiska uppgifter
Huvudupphovsmän: Iwamoto, Marian, Wenning, Larissa A., Petry, Amelia S., Laethem, Martine, De Smet, Marina, Kost, James T., Breidinger, Sheila A., Mangin, Eric C., Azrolan, Neal, Greenberg, Howard E., Haazen, Wouter, Stone, Julie A., Gottesdiener, Keith M., Wagner, John A.
Materialtyp: Artigo
Språk:Inglês
Publicerad: American Society for Microbiology (ASM) 2008
Ämnen:
Pharmacology
Länkar:https://ncbi.nlm.nih.gov/pmc/articles/PMC2592871/
https://ncbi.nlm.nih.gov/pubmed/18838589
https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01543-07
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