Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir

Raltegravir is a novel human immunodeficiency virus type 1 (HIV-1) integrase strand transfer inhibitor with potent in vitro activity against HIV-1 (95% inhibitory concentration = 31 nM in 50% human serum). The possible effects of ritonavir and efavirenz on raltegravir pharmacokinetics were separatel...

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Bibliographic Details
Main Authors:	Iwamoto, Marian, Wenning, Larissa A., Petry, Amelia S., Laethem, Martine, De Smet, Marina, Kost, James T., Breidinger, Sheila A., Mangin, Eric C., Azrolan, Neal, Greenberg, Howard E., Haazen, Wouter, Stone, Julie A., Gottesdiener, Keith M., Wagner, John A.
Format:	Artigo
Language:	Inglês
Published:	American Society for Microbiology (ASM) 2008
Subjects:	Pharmacology
Online Access:	https://ncbi.nlm.nih.gov/pmc/articles/PMC2592871/ https://ncbi.nlm.nih.gov/pubmed/18838589 https://ncbi.nlm.nih.govhttp://dx.doi.org/10.1128/AAC.01543-07
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Minimal Effects of Ritonavir and Efavirenz on the Pharmacokinetics of Raltegravir

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